Evidence map›Paper›PMID 25834321›Full record

ArticleWorld journal of gastroenterology2015

Hepatectomy with primary closure of common bile duct for hepatolithiasis combined with choledocholithiasis.

Chang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Qi-Fan Qin, Wei-Ming Yu

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. LIVER RESECTION FOR NON-ORIENTAL HEPATOLITHIASIS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chang-Ku JiaChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Jie WengChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
You-Ke ChenChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Qing-Zhuang YangChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Yu FuChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Qi-Fan QinChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Wei-Ming YuChang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Department of Hepatobiliary Pancreatic Surgery, The Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan Province, China.
Hainan Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the feasibility of hepatectomy and primary closure of common bile duct for intrahepatic and extrahepatic calculi.

methodsFrom January 2008 to May 2013, anatomic hepatectomy followed by biliary tract exploration without biliary drainage (non-drainage group) was performed in 43 patients with intrahepatic and extrahepatic calculi. After hepatectomy, flexible choledochoscopy was used to extract residual stones and observe the intrahepatic bile duct and common bile duct (CBD) for determination of biliary stricture and dilatation. Function of the sphincter of Oddi was determined by manometry of the CBD. Primary closure of the CBD without T-tube drainage or bilioenteric anastomosis was performed when there was no biliary stricture or sphincter of Oddi dysfunction. Dexamethasone and anisodamine were intravenously injected 2-3 d after surgery to prevent postoperative retrograde infection due to intraoperative bile duct irrigation, and to maintain relaxation of the sphincter of Oddi, respectively. During the same period, anatomic hepatectomy followed by biliary tract exploration with biliary drainage (drainage group) was performed in 48 patients as the control group. Postoperative complications and hospital stay were compared between the two groups.

resultsThere was no operative mortality in either group of patients. Compared to intrahepatic and extrabiliary drainage, hepatectomy with primary closure of the CBD (non-drainage) did not increase the incidence of complications, including residual stones, bile leakage, pancreatitis and cholangitis (P > 0.05). Postoperative hospital stay and costs were nevertheless significantly less in the non-drainage group than in the drainage group. The median postoperative hospital stay was shorter in the non-drainage group than in the drainage group (11.2 ± 2.8 d vs 15.4 ± 2.1 d, P = 0.000). The average postoperative cost of treatment was lower in the non-drainage group than in the drainage group (29325.6 ± 5668.2 yuan vs 32933.3 ± 6235.1 yuan, P = 0.005).

conclusionHepatectomy followed by choledochoendoscopic stone extraction without biliary drainage is a safe and effective treatment of hepatolithiasis combined with choledocholithiasis.

Indexed as

HepatectomyAdultAgedAnti-Inflammatory Agents, Non-SteroidalCholedocholithiasisCommon Bile DuctCost-Benefit AnalysisCost SavingsDexamethasoneDrainageFeasibility StudiesFemaleGlucocorticoidsHospital CostsHumansLength of StayanisodamineAnti-Inflammatory Agents, Non-SteroidalDexamethasoneGlucocorticoidsSolanaceous AlkaloidsBiliary drainageCholedocholithiasisHepatectomyHepatolithiasisPrimary closure

Identifiers

PMID25834321
PMCPMC4375578
OpenAlexW2003551293

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.