ArticleThe Journal of rheumatology2015
Predictors of longterm changes in body mass index in rheumatoid arthritis.
Article in The Journal of rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Construction and Use of Body Weight Measures from Administrative Data in a Large National Health System: A Systematic Review.Obesity (Silver Spring, Md.) · 2020Pooled it
- Statistical methods for analyzing change over time of continuous outcomes in observational health studies: a scoping review of suggested approaches.Systematic reviews · 2026Article
- Recent advances in methotrexate pharmacology and potential therapeutic uses in age-related cardiometabolic and neurodegenerative diseases.Pharmacological reviews · 2026Review
- Article
- Cachexia Prevalence in a Population of Moroccan Women with Rheumatoid Arthritis.Mediterranean journal of rheumatology · 2023Article
- Time to Deal with Rheumatoid Cachexia: Prevalence, Diagnostic Criteria, Treatment Effects and Evidence for Management.Mediterranean journal of rheumatology · 2022Review
- Deriving Weight From Big Data: Comparison of Body Weight Measurement-Cleaning Algorithms.JMIR medical informatics · 2022Article
- Body mass index trend and variability in rheumatoid arthritis.Clinical rheumatology · 2022Article
- Modified Diet Use in Adults with Temporomandibular Disorders related to Rheumatoid Arthritis: A Systematic Review.Mediterranean journal of rheumatology · 2020Review
- Obesity, Weight Loss, and Progression of Disability in Rheumatoid Arthritis.Arthritis care & research · 2018Article
- Non-obese visceral adiposity is associated with the risk of atherosclerosis in Japanese patients with rheumatoid arthritis: a cross-sectional study.Rheumatology international · 2018Article
- Body Mass Index, Weight Loss, and Cause-Specific Mortality in Rheumatoid Arthritis.Arthritis care & research · 2018Observational
- Changes in Body Mass Related to the Initiation of Disease-Modifying Therapies in Rheumatoid Arthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2016Article
- The Obesity Epidemic and Consequences for Rheumatoid Arthritis Care.Current rheumatology reports · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveLow body mass index (BMI) is a risk factor for poor longterm outcomes in rheumatoid arthritis (RA). The purpose of this study was to identify factors associated with longterm changes in BMI.
methodsSubjects with RA from the Veterans Affairs (VA) Rheumatoid Arthritis (VARA) Registry (n = 1474) were studied. Information on inflammatory markers, presence of erosions, and smoking status were extracted from the VARA database. BMI was extracted from VA electronic medical records within 14 days of each visit date. VA pharmacy records were queried to identify prescriptions for specific RA therapies within 1 month of the visit date. We used robust generalized estimating equations marginal regression models to calculate independent associations between clinical variables and BMI over time. Similar models determined predictors of change in weight and risk of weight loss over the subsequent study observation period.
resultsIncreasing age, active smoking, and the presence of erosions at baseline were associated with lower BMI. Weight decreased over time among older adults. Factors associated with greater reductions in BMI over time and a greater risk of weight loss were higher inflammatory markers, smoking, older age, higher BMI, and less subsequent improvement in inflammation. Methotrexate use was associated with a lower risk of weight loss. The use of prednisone or anti-tumor necrosis factor therapies was not associated with change in BMI or the risk of weight loss independent of other factors.
conclusionGreater age, greater inflammatory activity, and active smoking are associated with greater weight loss in RA over time.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.