ArticleArchives of disease in childhood. Fetal and neonatal edition2015
Neurodevelopmental outcomes following late and moderate prematurity: a population-based cohort study.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 127 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Family Integrated Care (FICare) in Level II NICUs: An Innovative Program for Alberta
Child Developmental Health, Maternal Psychosocial Distress, and Health System Costs At 18 Months Corrected Age: Effectiveness of a Cluster Randomized Controlled Trial of Family Integrated Care in Level II NICUs
Who cites it
127 citing papers in PubMed, 6 syntheses or guidelines pooled it, 271 citations in OpenAlex.
- Cerebrovascular autoregulation and preterm brain injury: a systematic review and meta-analysis.Pediatric research · 2025Pooled it
- Sex differences in the effects of prematurity and/or low birthweight on neurodevelopmental outcomes: systematic review and meta-analyses.Biology of sex differences · 2023Pooled it
- Social-environmental moderators of neurodevelopmental outcomes in youth born preterm: A systematic review.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2021Pooled it
- Sleep and prematurity: sleep outcomes in preterm children and influencing factors.World journal of pediatrics : WJP · 2019Pooled it
- Association of Hypertensive Disorders of Pregnancy With Risk of Neurodevelopmental Disorders in Offspring: A Systematic Review and Meta-analysis.JAMA psychiatry · 2018Pooled it
- Acoustic Features, Parental Perception and Developmental Correlations of Crying in Preterm Infants: A Systematic Review and Meta-Analysis.Infancy : the official journal of the International Society on Infant StudiesPooled it
- Long-term growth effects of post-discharge formula in moderate-to-late preterm infants: follow-up at 24 months corrected age of a randomized controlled trial.European journal of clinical nutrition · 2026Trial
- Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT.Pediatric research · 2025Trial
- Two-year follow-up of infant and maternal outcomes after planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): A randomised controlled trial.BJOG : an international journal of obstetrics and gynaecology · 2022Trial
- Randomised trial of cord clamping at very preterm birth: outcomes at 2 years.Archives of disease in childhood. Fetal and neonatal edition · 2020Trial
- Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT.Health technology assessment (Winchester, England) · 2020Trial
- Trial
- The Speed of Increasing milk Feeds: a randomised controlled trial.BMC pediatrics · 2017Trial
- Association between breastfeeding and neurodevelopmental outcomes after late preterm birth.Pregnancy (Hoboken, N.J.) · 2026Article
- Article
- The effects of the pandemic burden on early developmental outcomes in preterm children aged 0-3 years: a cross-sectional study.Child and adolescent psychiatry and mental health · 2026Article
- Parental Involvement in Decision-Making About Planned Late Preterm and Early Term Birth (The "PIP" Study): Part 1-A Reflexive Thematic Analysis of Interviews With Parents.Birth (Berkeley, Calif.) · 2026Article
- A quality improvement approach to growth in moderate and late preterm infants in small NICUs.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Exploring ocular fundus morphology in relation to growth in adolescents born moderate-to-late preterm.Acta ophthalmologica · 2026Article
- A Retrospective Study of High-Risk Infants: Insights From a Regional Hospital in Victoria, Australia.Journal of paediatrics and child health · 2026Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThere is a paucity of data relating to neurodevelopmental outcomes in infants born late and moderately preterm (LMPT; 32(+0)-36(+6) weeks). This paper present the results of a prospective, population-based study of 2-year outcomes following LMPT birth.
design1130 LMPT and 1255 term-born children were recruited at birth. At 2 years corrected age, parents completed a questionnaire to assess neurosensory (vision, hearing, motor) impairments and the Parent Report of Children's Abilities-Revised to identify cognitive impairment. Relative risks for adverse outcomes were adjusted for sex, socio-economic status and small for gestational age, and weighted to account for over-sampling of term-born multiples. Risk factors for cognitive impairment were explored using multivariable analyses.
resultsParents of 638 (57%) LMPT infants and 765 (62%) controls completed questionnaires. Among LMPT infants, 1.6% had neurosensory impairment compared with 0.3% of controls (RR 4.89, 95% CI 1.07 to 22.25). Cognitive impairments were the most common adverse outcome: LMPT 6.3%; controls 2.4% (RR 2.09, 95% CI 1.19 to 3.64). LMPT infants were at twice the risk for neurodevelopmental disability (RR 2.19, 95% CI 1.27 to 3.75). Independent risk factors for cognitive impairment in LMPT infants were male sex, socio-economic disadvantage, non-white ethnicity, preeclampsia and not receiving breast milk at discharge.
conclusionsCompared with term-born peers, LMPT infants are at double the risk for neurodevelopmental disability at 2 years of age, with the majority of impairments observed in the cognitive domain. Male sex, socio-economic disadvantage and preeclampsia are independent predictors of low cognitive scores following LMPT birth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.