Evidence map›Paper›PMID 25834122›Full record

ArticleSexually transmitted infections2015

High prevalence of sexually transmitted infections in pregnant adolescent girls in Tanzania: a multi-community cross-sectional study.

Adolfine Hokororo, Albert Kihunrwa, Pytsje Hoekstra, Samuel E Kalluvya, John M Changalucha, Daniel W Fitzgerald, Jennifer A Downs

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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  10. Prevalence and Genetic Characterization ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Adolfine HokororoDepartment of Pediatrics, Bugando Medical Centre, Mwanza, Tanzania Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Albert KihunrwaCatholic University of Health and Allied Sciences, Mwanza, Tanzania Department of Obstetrics and Gynecology, Bugando Medical Centre, Mwanza, Tanzania.
Pytsje HoekstraVrije Universiteit, Amsterdam, the Netherlands.
Samuel E KalluvyaCatholic University of Health and Allied Sciences, Mwanza, Tanzania Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania.
John M ChangaluchaNational Institute for Medical Research, Mwanza, Tanzania.
Daniel W FitzgeraldDepartment of Medicine, Center for Global Health, Weill Cornell Medical College, New York, New York, USA.
Jennifer A DownsCatholic University of Health and Allied Sciences, Mwanza, Tanzania Department of Medicine, Bugando Medical Centre, Mwanza, Tanzania Department of Medicine, Center for Global Health, Weill Cornell Medical College, New York, New York, USA.
Catholic University of Health and Allied Sciences · TZBugando Medical Centre · TZCornell University · USNational Institute for Medical Research · TZVrije Universiteit Amsterdam · NL

Funding

Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
TUBERCULOSIS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW000018 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI JOHNSON, WARREN DOUGLAS · 1988 to 2012
$16.1M
Global Health Research Training in HIV and TuberculosisK24AI098627 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2012 to 2022
$1.8M
Schistosomiasis, Mucosal Immunity, and HIV SusceptibilityK23AI110238 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DOWNS, JENNIFER ALZOS · 2014 to 2018
$928k
FIC NIH HHS D43 TW000018FIC NIH HHS TW00018NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1 TR000457-06NIAID NIH HHS AI098627NIAID NIH HHS K23 AI110238NIAID NIH HHS K23AI110238NIAID NIH HHS K24 AI098627
6 · The paper itself

Abstract

backgroundLimited data document sexually transmitted infections (STIs) among pregnant adolescents in sub-Saharan Africa, where prenatal screening typically includes only HIV and syphilis. Given that HIV incidence in this population is among the world's highest, we sought to assess the prevalence and factors associated with STIs in a population of rural pregnant adolescents in Tanzania.

methodsWe enrolled 403 pregnant adolescent girls from 10 antenatal clinics near Mwanza, Tanzania. Girls answered structured interviews about sexual health and risk factors and were tested for six common STIs.

results199 girls (49.4%) had at least one STI. Herpes Simplex Virus- Type 2 was most prevalent (139 girls, 34.5%), followed by trichomoniasis (54 girls, 13.4%), chlamydia (46 girls, 11.4%), gonorrhoea (27 girls, 6.7%), syphilis (21 girls, 5.2%) and HIV (30 girls, 4.7%). Of note, 53/199 (26.6%) of girls with laboratory-proven STIs were asymptomatic. On multivariable analysis, the presence of any STI was associated with being in a long-term (as opposed to short-term) relationship (OR=2.6 (1.4 to 4.9) p=0.004), younger age at first sexual debut (OR=0.9 per year (0.8 to 0.99), p=0.034), increasing age difference between the girl and her partner (OR=1.1 (1.0 to 1.1) per year, p=0.03) and history of prior pregnancy (OR=1.6 (1.0 to 2.6), p=0.04).

conclusionsSTIs affected half of rural pregnant adolescents in Tanzania. Our work demonstrates the urgent need to incorporate routine STI testing into antenatal care in Tanzania to prevent morbidity and mortality in young girls and their babies. We also identify behavioural and demographic risk factors that can be used to target interventions to those at highest risk.

Indexed as

AdolescentCross-Sectional StudiesDiagnostic Tests, RoutineFemaleHumansPregnancyPregnancy Complications, InfectiousPrevalenceRural PopulationSexually Transmitted DiseasesSurveys and QuestionnairesTanzaniaYoung Adult

Identifiers

PMID25834122
PMCPMC4591089
OpenAlexW1981117519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.