ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Broad thorny ganglion cells: a candidate for visual pursuit error signaling in the primate retina.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 56 citations in OpenAlex.
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- Diversity and Feature Selectivity of Primate Retinal Ganglion Cells.Annual review of vision science · 2026Review
- Filter, Detector, Predictor: The expanding repertoire of retinal computation in vertebrates.Vision research · 2026Review
- Widespread Corticothalamic Connectivity Identifies the Inferior Pulvinar as a Central Node in Visual Network Architecture.bioRxiv : the preprint server for biology · 2026Article
- Surround motion modulates the encoding properties of primate retinal ganglion cells.Cell reports · 2026Article
- Cell-type specific repertoire of responses to natural scenes in primate retinal ganglion cells.Frontiers in cellular neuroscience · 2025Article
- Review
- From water to land: Evolution of photoreceptor circuits for vision in air.PLoS biology · 2024Article
- Retinal ganglion cells expressing CaM kinase II in human and nonhuman primates.The Journal of comparative neurology · 2022Article
- Origins of direction selectivity in the primate retina.Nature communications · 2022Article
- Satb1 expression in retinal ganglion cells of marmosets, macaques, and humans.The Journal of comparative neurology · 2022Article
- In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis.PloS one · 2022Article
- Retinal ganglion cells projecting to superior colliculus and pulvinar in marmoset.Brain structure & function · 2021Article
- Genetic interplay between transcription factor Pou4f1/Brn3a and neurotrophin receptor Ret in retinal ganglion cell type specification.Neural development · 2021Article
- Synaptic inputs to broad thorny ganglion cells in macaque retina.The Journal of comparative neurology · 2021Article
- Retinal Ganglion Cells-Diversity of Cell Types and Clinical Relevance.Frontiers in neurology · 2021Review
- An offset ON-OFF receptive field is created by gap junctions between distinct types of retinal ganglion cells.Nature neuroscience · 2021Article
- Neural Mechanisms of Visual Motion Anomalies in Autism: A Two-Decade Update and Novel Aetiology.Frontiers in neuroscience · 2021Review
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Functional analyses exist only for a few of the morphologically described primate ganglion cell types, and their correlates in other mammalian species remain elusive. Here, we recorded light responses of broad thorny cells in the whole-mounted macaque retina. They showed ON-OFF-center light responses that were strongly suppressed by stimulation of the receptive field surround. Spike responses were delayed compared with parasol ganglion cells and other ON-OFF cells, including recursive bistratified ganglion cells and A1 amacrine cells. The receptive field structure was shaped by direct excitatory synaptic input and strong presynaptic and postsynaptic inhibition in both ON and OFF pathways. The cells responded strongly to dark or bright stimuli moving either in or out of the receptive field, independent of the direction of motion. However, they did not show a maintained spike response either to a uniform background or to a drifting plaid pattern. These properties could be ideally suited for guiding movements involved in visual pursuit. The functional characteristics reported here permit the first direct cross-species comparison of putative homologous ganglion cell types. Based on morphological similarities, broad thorny ganglion cells have been proposed to be homologs of rabbit local edge detector ganglion cells, but we now show that the two cells have quite distinct physiological properties. Thus, our data argue against broad thorny cells as the homologs of local edge detector cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.