Evidence map›Paper›PMID 25833887›Full record

ReviewThe Journal of nutrition2015

Epigenetics of inflammation, maternal infection, and nutrition.

Kate J Claycombe, Catherine A Brissette, Othman Ghribi

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
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  5. Therapeutic nanoparticle safety in pregnancy: Bridging knowledge gaps with environmental insights and a translational roadmap.Journal of controlled release : official journal of the Controlled Release Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kate J ClaycombeUSDA-Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND; and kate.claycombe@ars.usda.gov.
Catherine A BrissetteDepartment of Basic Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND.
Othman GhribiDepartment of Basic Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND.
University of North Dakota · USAgricultural Research Service · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have demonstrated that epigenetic changes such as DNA methylation, histone modification, and chromatin remodeling are linked to an increased inflammatory response as well as increased risk of chronic disease development. A few studies have begun to investigate whether dietary nutrients play a beneficial role by modifying or reversing epigenetically induced inflammation. Results of these studies show that nutrients modify epigenetic pathways. However, little is known about how nutrients modulate inflammation by regulating immune cell function and/or immune cell differentiation via epigenetic pathways. This overview will provide information about the current understanding of the role of nutrients in the epigenetic control mechanisms of immune function.

Indexed as

Epigenesis, GeneticImmunityMaternal Nutritional Physiological PhenomenaAdultAnimalsChild DevelopmentCongresses as TopicDietFemaleFetal DevelopmentHumansInfantInfant, NewbornLactationMalePregnancyepigeneticsimmunityinflammationmacrophagesnutrientsobesity

Identifiers

PMID25833887
PMCPMC4410493
OpenAlexW2089080243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.