ArticleProceedings. Biological sciences2015
Genome-wide association mapping in a wild avian population identifies a link between genetic and phenotypic variation in a life-history trait.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- Evolution under the city's shadow: reproductive divergence of urban and rural great tits revealed by a common garden experiment.Evolution letters · 2026Article
- On the genetic origins of phenotypes in genome-wide association studies: the SAFE-hBMC bioinformatics · 2026Article
- Accounting for population structure and data quality in demographic inference with linkage disequilibrium methods.Nature communications · 2025Article
- Inheritance of Material Wealth in a Natural Population.Ecology letters · 2024Article
- Strongly deleterious mutations influence reproductive output and longevity in an endangered population.Nature communications · 2024Article
- The battle of the sexes in humans is highly polygenic.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genetic and epigenetic differentiation in response to genomic selection for avian lay date.Evolutionary applications · 2024Article
- Genetic architecture of dispersal behaviour in the post-harvest pest and model organism Tribolium castaneum.Heredity · 2023Article
- Population genomics for wildlife conservation and management.Molecular ecology · 2021Review
- The March of the Beetles: Epistatic Components Dominate Divergence in Dispersal Tendency in Tribolium castaneum.The Journal of heredity · 2020Article
- Polygenic basis for adaptive morphological variation in a threatened Aotearoa | New Zealand bird, the hihi (Proceedings. Biological sciences · 2020Article
- The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries).PLoS genetics · 2019Article
- Animal models with group-specific additive genetic variances: extending genetic group models.Genetics, selection, evolution : GSE · 2019Article
- Functional Validation of Candidate Genes Detected by Genomic Feature Models.G3 (Bethesda, Md.) · 2018Article
- Genetics of dispersal.Biological reviews of the Cambridge Philosophical Society · 2018Review
- Article
- Insights into the genetic architecture of morphological traits in two passerine bird species.Heredity · 2017Article
- Article
- Environment-Dependent Genotype-Phenotype Associations in Avian Breeding Time.Frontiers in genetics · 2017Article
- Accumulation of Deleterious Mutations Near Sexually Antagonistic Genes.G3 (Bethesda, Md.) · 2016Article
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the genetic basis of traits involved in adaptation is a major challenge in evolutionary biology but remains poorly understood. Here, we use genome-wide association mapping using a custom 50 k single nucleotide polymorphism (SNP) array in a natural population of collared flycatchers to examine the genetic basis of clutch size, an important life-history trait in many animal species. We found evidence for an association on chromosome 18 where one SNP significant at the genome-wide level explained 3.9% of the phenotypic variance. We also detected two suggestive quantitative trait loci (QTLs) on chromosomes 9 and 26. Fitness differences among genotypes were generally weak and not significant, although there was some indication of a sex-by-genotype interaction for lifetime reproductive success at the suggestive QTL on chromosome 26. This implies that sexual antagonism may play a role in maintaining genetic variation at this QTL. Our findings provide candidate regions for a classic avian life-history trait that will be useful for future studies examining the molecular and cellular function of, as well as evolutionary mechanisms operating at, these loci.
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