ReviewEuropean journal of pediatrics2015
Vitamin D in childhood and adolescence: an expert position statement.
Review in European journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03475225 (Effect of the Treatment of Vitamin D Deficiency in Drug-resistant Epilepsy), which is not on this map. Cited by 72 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of the Treatment of Vitamin D Deficiency in Drug-resistant Epilepsy
Who cites it
72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Vitamin D and Stroke: Effects on Incidence, Severity, and Outcome and the Potential Benefits of Supplementation.Frontiers in neurology · 2020Pooled it
- Vitamin D Food Fortification and Nutritional Status in Children: A Systematic Review of Randomized Controlled Trials.Nutrients · 2019Pooled it
- Vitamin D in European children-statement from the European Academy of Paediatrics (EAP).European journal of pediatrics · 2017Guideline
- The Effect of Vitamin D3 Supplementation on Vitamin D Status and Associated Health Outcomes in Children: A Randomized Controlled Trial.The Journal of nutrition · 2026Trial
- Bone Response to High-Intensity Interval Training versus Moderate-Intensity Continuous Training in Adolescents with Obesity.Obesity facts · 2022Trial
- Phosphate Concentrations and Modifying Factors in Healthy Children From 12 to 24 Months of Age.The Journal of clinical endocrinology and metabolism · 2021Trial
- Trial
- Trial
- Population Serum 25-Hydroxyvitamin D Status in Kazakhstan: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2026Review
- Knowledge, attitudes and behaviours towards vitamin D and sun exposure of parents of infants and young children and health professionals in New Zealand.Nutrition and health · 2026Article
- Assessment of Vitamin D Deficiency and its Association with Musculoskeletal Pain in Children.Journal of pharmacy & bioallied sciences · 2025Article
- Is there a correlation between the severity of symptoms and vitamin D levels in pregnancy with hyperemesis gravidarum?Turkish journal of obstetrics and gynecology · 2025Article
- The Management of Bone Defects in Rett Syndrome.Calcified tissue international · 2025Review
- Review
- Investigating Vitamin D-Binding Protein's Role in Childhood Health and Development.International journal of molecular sciences · 2024Review
- Prevalence of the Double Burden of Malnutrition among Adolescents: Associations with Lifestyle Behaviors and Clusters of Social Determinants.Children (Basel, Switzerland) · 2024Article
- Bone health: Quality versus quantity.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Pediatric acute-onset neuropsychiatric syndrome and pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections: a delphi study and consensus document about definition, diagnostic criteria, treatment and follow-up.Frontiers in immunology · 2024Article
- Vitamin D status, vitamin D receptor, CYP2R1, and CYP24A1 profiles in children.Frontiers in nutrition · 2024Article
- IGF1 Genetic Polymorphism and the Association between Vitamin D Status and BMI Percentiles in Children.Children (Basel, Switzerland) · 2023Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledVitamin D is a key hormone in the regulation of calcium and phosphorus metabolism and plays a pivotal role in bone health, particularly during pediatric age when nutritional rickets and impaired bone mass acquisition may occur. Great interest has been placed in recent years on vitamin D's extraskeletal actions. However, while recent data suggest a possible role of vitamin D in the pathogenesis of several pathological conditions, including infectious and autoimmune diseases, the actual impact of vitamin D status on the global health of children and adolescents, other than bone, remains a subject of debate. In the meantime, pediatricians still need to evaluate the determinants of vitamin D status and consider vitamin D supplementation in children and adolescents at risk of deficiency. This review is the result of an expert meeting that was held during the congress "Update on vitamin D and bone disease in childhood" convened in Pisa, Italy, in May 2013.
conclusionThe collaboration of the international group of experts produced this "state of the art" review on vitamin D in childhood and adolescence. After dealing with vitamin D status and its determinants, the review outlines the current debate on vitamin D's health benefits, concluding with a practical approach to vitamin D supplementation during childhood and adolescence. WHAT IS KNOWN: • Vitamin D deficiency is a worldwide health problem. • Vitamin D deficiency affects not only musculoskeletal health but also a potentially wide range of acute and chronic diseases. What is New: • We reviewed the literature focusing on randomized controlled trials of vitamin D supplementation during childhood and adolescence. • This review will help pediatricians to appreciate the clinical relevance of an adequate vitamin D status and it will provide a practical approach to vitamin D supplementation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.