Evidence map›Paper›PMID 25833054›Full record

ArticleJournal of virology2015

Us9-Independent Axonal Sorting and Transport of the Pseudorabies Virus Glycoprotein gM.

R Kratchmarov, L W Enquist, M P Taylor

Abstract read
In one paragraph

Article in Journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R KratchmarovDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
L W EnquistDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
M P TaylorDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA Department of Microbiology and Immunology, Montana State University, Bozeman, Montana, USA mptaylor@montana.edu.

Funding

Pilot Grants ProgramP30GM110732 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2014 to 2018
$5.4M
Center for Zoonotic and Emerging Infectious DiseasesP20GM103500 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T · 2012 to 2013
$4.2M
Genetic Analysis of Herpesvirus Tropism and VirulenceR37NS033506 · NINDS · PRINCETON UNIVERSITY · PI ENQUIST, LYNN W. · 2005 to 2020
$4.1M
GENETIC ANALYSIS OF HERPESVIRUS TROPISM AND VIRULENCER01NS033506 · NINDS · PRINCETON UNIVERSITY · PI ENQUIST, LYNN W. · 1995 to 2016
$3.7M
Neuronal Spread of Herpesvirus InfectionR01NS060699 · NINDS · PRINCETON UNIVERSITY · PI ENQUIST, LYNN W. · 2008 to 2017
$3.6M
Encryption methods and software for privacy-preserving analysis of biomedical dataU01EB023685 · NIBIB · TRUSTEES OF INDIANA UNIVERSITY · PI TANG, HAIXU, WANG, XIAOFENG · 2016 to 2018
$1.4M
Understanding the bottleneck on axon-to-cell spread of alphaherpesvirusesK22AI106948 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI TAYLOR, MATTHEW P. · 2014 to 2015
$268k
NIAID NIH HHS K22 AI106948NIBIB NIH HHS U01 EB023685NIGMS NIH HHS 8P20GM103500-10NIGMS NIH HHS GM110732NIGMS NIH HHS P20 GM103500NIGMS NIH HHS P30 GM110732NINDS NIH HHS R01 NS033506NINDS NIH HHS R01 NS060699NINDS NIH HHS R01 NS060699-03NINDS NIH HHS R37 NS033506NINDS NIH HHS R37 NS033506-16PHS HHS K22106948-01A1
6 · The paper itself

Abstract

Axonal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the viral protein Us9. Here we identify a Us9-independent mechanism for axonal localization of viral glycoprotein M (gM). We detected gM-mCherry assemblies transporting in the anterograde direction in axons. Furthermore, unlabeled gM, but not glycoprotein B, was detected by Western blotting in isolated axons during Us9-null PRV infection. These results suggest that gM differs from other viral proteins regarding axonal transport properties.

Indexed as

Protein TransportAxonsHerpesvirus 1, SuidIntracellular Signaling Peptides and ProteinsLipoproteinsPhosphoproteinsViral Envelope ProteinsViral ProteinsIntracellular Signaling Peptides and ProteinsLipoproteinsPhosphoproteinspseudorabies virus glycoproteinsUS9 protein, Suid herpesvirus 1Viral Envelope ProteinsViral Proteins

Identifiers

PMID25833054
PMCPMC4474295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.