ArticleThe Journal of physiology2015
The influence of sensory afferent input on local motor cortical excitatory circuitry in humans.
Article in The Journal of physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Technical development of transcutaneous electrical nerve inhibition using medium-frequency alternating current.Journal of neuroengineering and rehabilitation · 2018Trial
- Pain suppresses corticospinal excitability, independent of tactile afferent inhibition.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- The Effect of 5G Mobile Phone Electromagnetic Exposure on Corticospinal and Intracortical Excitability in Healthy Adults: A Randomized Controlled Pilot Study.Brain sciences · 2025Article
- The Somatosensory Cortex and Body Representation: Updating the Motor System during a Visuoproprioceptive Cue Conflict.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Modulation of Motor Cortical Inhibition and Facilitation by Touch Sensation from the Glabrous Skin of the Human Hand.eNeuro · 2024Article
- Case report: High-frequency repetitive transcranial magnetic stimulation for treatment of hereditary spastic paraplegia type 11.Frontiers in neurology · 2023Article
- Plasticity of face-hand sensorimotor circuits after a traumatic brachial plexus injury.Frontiers in neuroscience · 2023Article
- Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Review
- Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites.Brain sciences · 2021Article
- Putting the "Sensory" Into Sensorimotor Control: The Role of Sensorimotor Integration in Goal-Directed Hand Movements After Stroke.Frontiers in integrative neuroscience · 2019Review
- Verbal working memory modulates afferent circuits in motor cortex.The European journal of neuroscience · 2018Article
- Reduced Short-Latency Afferent Inhibition in Prefrontal but not Motor Cortex and Its Association With Executive Function in Schizophrenia: A Combined TMS-EEG Study.Schizophrenia bulletin · 2018Article
- Reduced Prefrontal Short-Latency Afferent Inhibition in Older Adults and Its Relation to Executive Function: A TMS-EEG Study.Frontiers in aging neuroscience · 2017Article
- A combined TMS-EEG study of short-latency afferent inhibition in the motor and dorsolateral prefrontal cortex.Journal of neurophysiology · 2016Article
- Paired Stimulation to Promote Lasting Augmentation of Corticospinal Circuits.Neural plasticity · 2016Review
- The Neurobiological Grounding of Persistent Stuttering: from Structure to Function.Current neurology and neuroscience reports · 2015Review
- Pulse Duration as Well as Current Direction Determines the Specificity of Transcranial Magnetic Stimulation of Motor Cortex during Contraction.Brain stimulationArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
In human, sensorimotor integration can be investigated by combining sensory input and transcranial magnetic stimulation (TMS). Short latency afferent inhibition (SAI) refers to motor cortical inhibition 20-25 ms after median nerve stimulation. We investigated the interaction between SAI and short-interval intracortical facilitation (SICF), an excitatory motor cortical circuit. Seven experiments were performed. Contrary to expectations, SICF was facilitated in the presence of SAI (SICF(SAI)). This effect is specific to SICF since there was no effect at SICF trough 1 when SICF was absent. Furthermore, the facilitatory SICF(SAI) interaction increased with stronger SICF or SAI. SAI and SICF correlated between individuals, and this relationship was maintained when SICF was delivered in the presence of SAI, suggesting an intrinsic relationship between SAI and SICF in sensorimotor integration. The interaction was present at rest and during muscle contraction, had a broad degree of somatotopic influence and was present in different interneuronal SICF circuits induced by posterior-anterior and anterior-posterior current directions. Our results are compatible with the finding that projections from sensory to motor cortex terminate in both superficial layers where late indirect (I-) waves are thought to originate, as well as deeper layers with more direct effect on pyramidal output. This interaction is likely to be relevant to sensorimotor integration and motor control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.