ArticleInternational journal of clinical pharmacy2015
Primary non-adherence in Portugal: findings and implications.
Article in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reasons for Primary Medication Nonadherence: A Systematic Review and Metric Analysis.Journal of managed care & specialty pharmacy · 2018Pooled it
- Impact of Different Onboarding Strategies on Low Adoption and Engagement With a Self-Monitoring and Management App for Chronic Musculoskeletal Pain: Prospective Study.JMIR mHealth and uHealth · 2026Article
- Adherence to pharmacological therapy for hypertension in Portugal: a health professionals focus groups study.BMC primary care · 2025Article
- Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Review
- Using the national electronic prescription system to determine the primary non-adherence to medication in the Czech Republic.Frontiers in pharmacology · 2023Article
- Exploring Muslims' Health-Related Behaviours in Portugal: Any Impact on Quotidian Community Pharmacy Practice?Pharmacy (Basel, Switzerland) · 2022Article
- Quality of Life, Sexual Functioning and Chronic Disease: A Comparative Study with Portuguese Women without Chronic Disease, and Women with Diabetes Type 1 and 2, and Arterial Hypertension.International journal of sexual health : official journal of the World Association for Sexual Health · 2022Article
- Factors Associated with HIV and Vulnerability Contexts for Women in Brazil.Archives of sexual behavior · 2021Article
- Awareness about barriers to medication adherence in cardiovascular patients and strategies used in clinical practice by Portuguese clinicians: a nationwide study.International journal of clinical pharmacy · 2021Review
- Is Prescription Nonredemption a Source of Poor Health Among the Roma? Cross-Sectional Analysis of Drug Consumption Data From the National Health Insurance Fund of Hungary.Frontiers in pharmacology · 2021Article
- A Nationwide Cross-Sectional Study of Self-Reported Adherence and Factors Associated with Analgesic Treatment in People with Chronic Pain.Journal of clinical medicine · 2020Article
- Medication Adherence In Patients With Arterial Hypertension: The Relationship With Healthcare Systems' Organizational Factors.Patient preference and adherence · 2019Article
- The Great Recession and inequalities in access to health care: a study of unemployment and unmet medical need in Europe in the economic crisis.International journal of epidemiology · 2018Article
- Effect of different methods for estimating persistence and adherence to new glucose-lowering drugs: results of an observational, inception cohort study in Portugal.Patient preference and adherence · 2018Article
- Initial medication non-adherence: prevalence and predictive factors in a cohort of 1.6 million primary care patients.British journal of clinical pharmacology · 2017Article
- Effects of economic recession on elderly patients' perceptions of access to health care and medicines in Portugal.International journal of clinical pharmacy · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPortugal is currently facing a serious economic and financial crisis, which is dictating some important changes in the health care sector. Some of these measures may potentially influence patients' access to medication and consequently adherence, which will ultimately impact on health status, especially in chronic patients.
aimsThis study aimed at providing a snapshot of adherence in patients with chronic conditions in Portugal between March and April 2012.
settingCommunity pharmacy in Portugal.
methodA cross-sectional pilot study was undertaken, where patients were recruited via community pharmacies to a questionnaire study evaluating the number of prescribed and purchased drugs and, when these figures were inconsistent, the reasons for this.
main outcome measuresPrimary and secondary adherence measures. Failing to purchase prescription items was categorized as primary nonadherence. Secondary nonadherence was attributed to purchasing prescription items, but not taking medicines as prescribed.
resultsData were collected from 375 patients. Primary nonadherence was identified in 22.8 % of patients. Regardless of the underlying condition, the most commonly reported reason for primary non-adherence was having spare medicines at home ("leftovers"), followed by financial problems. The latter appeared to be related to the class of medicines prescribed. Primary non-adherence was associated with low income (<475 <euro>/month; p = 0.026). Secondary non-adherence, assessed by the 7-MMAS was detected in over 50 % of all patients, where unintentional nonadherence was higher than intentional nonadherence across all disease conditions.
conclusionThis study revealed that more than one fifth of chronic medication users report primary nonadherence (22.8 %) and more than 50 % report secondary nonadherence. Data indicates that the existence of spare medicines and financial constraints occurred were the two most frequent reasons cited for nonadherence (47, 6-64, 8 and 19-45.5 %, depending on the major underlying condition, respectively).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.