Evidence map›Paper›PMID 25832490›Full record

ArticleEuropean journal of nutrition2016

Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population.

Caterina Vacchi-Suzzi, Roxanne Karimi, Danielle Kruse, Susan M Silbernagel, Keith E Levine, Diane S Rohlman, Jaymie R Meliker

Abstract read
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In one paragraph

Article in European journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Caterina Vacchi-SuzziProgram in Public Health, Department of Preventive Medicine, Stony Brook University, Stony Brook, NY, 11794, USA. caterina.vacchi-suzzi@stonybrookmedicine.edu.
Roxanne KarimiSchool of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794, USA.
Danielle KruseSchool of Medicine, Stony Brook University, Stony Brook, NY, 11794, USA.
Susan M SilbernagelDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
Keith E LevineTrace Inorganics Department, Technologies for Industry and the Environment, RTI International, Research Triangle Park, NC, 27709, USA.
Diane S RohlmanOccupational and Environmental Health, University of Iowa, Iowa City, IA, 52242, USA.
Jaymie R MelikerProgram in Public Health, Department of Preventive Medicine, Stony Brook University, Stony Brook, NY, 11794, USA.
Stony Brook University · USRTI International · USUniversity of Iowa · USUniversity of Washington · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Urinary cadmium and risk of breast cancerR01ES019209 · NIEHS · STATE UNIVERSITY NEW YORK STONY BROOK · PI MELIKER, JAYMIE R · 2011 to 2014
$1.9M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS R01 ES019209
6 · The paper itself

Abstract

backgroundNeurodevelopmental effects of omega-3 fatty acids and mercury from fish consumption have been characterized in children. In contrast, neurobehavioral outcomes associated with fish are not well studied in adults.

objectiveThis study of avid seafood consumers on Long Island (NY, USA) sought to define associations between mercury, seafood consumption, omega-3 fatty acids and neurobehavioral outcomes.

methodsA computer-based test system was used to assess neurobehavioral function. Blood total Hg (Hg) and omega-3 index were measured in 199 adult avid seafood eaters, who also completed the neurobehavioral assessment and an extensive food and fish frequency and demographic questionnaire.

resultsFor most of the outcomes considered, neither Hg nor omega-3 index was associated with neurobehavioral outcomes after adjustment for key confounding variables. Fish consumption, however, was associated with decreased odds of both self-reported fatigue (OR 0.85; 95 % CI 0.72, 1.01) and a constellation of neurologic symptoms (OR 0.79; 95 % CI 0.66, 0.96).

conclusionsResults from our study provide little evidence that omega-3 fatty acids or Hg is associated with cognitive function in adult avid seafood consumers. Larger studies are needed to confirm our finding of associations between fish consumption and decreased self-reported fatigue and neurologic impairment.

Indexed as

AdultAnimalsCognitionDepressionFatty Acids, Omega-3FemaleFishesFood ContaminationHumansLinear ModelsLogistic ModelsMaleMercuryMiddle AgedNervous System DiseasesNew YorkFatty Acids, Omega-3MercurySeleniumMercuryMethylmercuryn-3 fatty acidsNeurobehavioral testNeurological testOmega-3

Identifiers

PMID25832490
OpenAlexW2032810828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.