Evidence map›Paper›PMID 25832481›Full record

Trial reportHuman genetics2015

West Eurasian mtDNA lineages in India: an insight into the spread of the Dravidian language and the origins of the caste system.

Malliya Gounder Palanichamy, Bikash Mitra, Cai-Ling Zhang, Monojit Debnath, Gui-Mei Li, Hua-Wei Wang, Suraksha Agrawal, Tapas Kumar Chaudhuri, Ya-Ping Zhang

Abstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Human genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Mitochondrial DNA (CA)Genetica · 2022
    Article
  6. Mitogenomics of modern Mongolic-speaking populations.Molecular genetics and genomics : MGG · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. States and their genetic consequences in central Africa.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Malliya Gounder PalanichamyLaboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming, 650 091, Yunnan, China, empalani@yahoo.com.
Bikash Mitra
Cai-Ling Zhang
Monojit Debnath
Gui-Mei Li
Hua-Wei Wang
Suraksha Agrawal
Tapas Kumar Chaudhuri
Ya-Ping Zhang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no indication from the previous mtDNA studies that west Eurasian-specific subclades have evolved within India and played a role in the spread of languages and the origins of the caste system. To address these issues, we have screened 14,198 individuals (4208 from this study) and analyzed 112 mitogenomes (41 new sequences) to trace west Eurasian maternal ancestry. This has led to the identification of two autochthonous subhaplogroups--HV14a1 and U1a1a4, which are likely to have originated in the Dravidian-speaking populations approximately 10.5-17.9 thousand years ago (kya). The carriers of these maternal lineages might have settled in South India during the time of the spread of the Dravidian language. In addition to this, we have identified several subsets of autochthonous U7 lineages, including U7a1, U7a2b, U7a3, U7a6, U7a7, and U7c, which seem to have originated particularly in the higher-ranked caste populations in relatively recent times (2.6-8.0 kya with an average of 5.7 kya). These lineages have provided crucial clues to the differentiation of the caste system that has occurred during the recent past and possibly, this might have been influenced by the Indo-Aryan migration. The remaining west Eurasian lineages observed in the higher-ranked caste groups, like the Brahmins, were found to cluster with populations who possibly arrived from west Asia during more recent times.

Indexed as

LanguagePolymorphism, Single NucleotideSocial ClassAnthropology, CulturalDNA, MitochondrialFemaleHumansIndiaMaleDNA, Mitochondrial

Identifiers

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.