Evidence map›Paper›PMID 25832337›Full record

ArticleThe American journal of clinical nutrition2015

Association between birth weight and objectively measured sedentary time is mediated by central adiposity: data in 10,793 youth from the International Children's Accelerometry Database.

Maria Hildebrand, Elin Kolle, Bjørge H Hansen, Paul J Collings, Katrien Wijndaele, Katarzyna Kordas, Ashley R Cooper, Lauren B Sherar, Lars Bo Andersen, Luis B Sardinha and 5 more

Erratum issuedAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Prenatal, birth and early life predictors of sedentary behavior in young people: a systematic review.The international journal of behavioral nutrition and physical activity · 2016
    Pooled it
  5. Article
  6. Gender differences in the distribution of children's physical activity: evidence from nine countries.The international journal of behavioral nutrition and physical activity · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Best (but oft-forgotten) practices: mediation analysis.The American journal of clinical nutrition · 2017
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Maria HildebrandFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Elin KolleFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Bjørge H HansenFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Paul J CollingsFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Katrien WijndaeleFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Katarzyna KordasFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Ashley R CooperFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Lauren B SherarFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Lars Bo AndersenFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Luis B SardinhaFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Susi KriemlerFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Pedro HallalFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Esther van SluijsFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
Ulf EkelundFrom the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway (MH, EK, BHH, LBA, and UE); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (PJC, KW, EvS, and UE); the School of Social and Community Medicine (KK) and the Centre for Exercise, Nutrition & Health Sciences, School for Policy Studies (ARC), University of Bristol, Bristol, United Kingdom; the School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom (LB Sherar); the Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark (LBA); the Department of Sport and Health, University of Lisbon, Lisbon, Portugal (LB Sardinha); the Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland (SK); and the Department of Physical Education, Federal University of Pelotas, Pelotas, Brazil (PH).
International Children’s Accelerometry Database (ICAD) Collaborators

Funding

British Heart Foundation FS/12/58/29709Cancer Research UKChief Scientist OfficeDepartment of HealthMedical Research Council G0501294Medical Research Council G0701877Medical Research Council MC_PC_15018Medical Research Council MC_U106179473Medical Research Council MC_UP_1001/2Medical Research Council MC_UU_12015/3Medical Research Council MC_UU_12015/4Medical Research Council MC_UU_12015/7Medical Research Council MR/K023187/1Wellcome Trust 095582Wellcome Trust 102215
6 · The paper itself

Abstract

backgroundBirth weight is an early correlate of disease later in life, and animal studies suggest that low birth weight is associated with reduced activity and increased sedentary time. Whether birth weight predicts later sedentary time in humans is uncertain.

objectivesWe examined the relation between birth weight and sedentary time in youth and examined whether this association was mediated by central adiposity.

designWe used pooled cross-sectional data from 8 observational studies conducted between 1997 and 2007 that consisted of 10,793 youth (boys: 47%) aged 6-18 y from the International Children's Accelerometry Database. Birth weight was measured in hospitals or maternally reported, sedentary time was assessed by using accelerometry (<100 counts/min), and abdominal adiposity (waist circumference) was measured according to WHO procedures. A mediation analysis with bootstrapping was used to analyze data.

resultsThe mean (±SD) time spent sedentary was 370 ± 91 min/d. Birth weight was positively associated with sedentary time (B = 4.04, P = 0.006) and waist circumference (B = 1.59, P < 0.001), whereas waist circumference was positively associated with sedentary time (B = 0.82, P < 0.001). Results of the mediation analysis showed a significant indirect effect of birth weight on sedentary time through waist circumference (B: 1.30; 95% bias-corrected CI: 0.94, 1.72), and when waist circumference was controlled for, the effect of birth weight on sedentary time was attenuated by 32% (B = 2.74, P = 0.06).

conclusionThe association between birth weight and sedentary time appears partially mediated by central adiposity, suggesting that both birth weight and abdominal adiposity may be correlates of sedentary time in youth.

Indexed as

AdiposityBirth WeightSedentary BehaviorAccelerometryAdolescentBody Mass IndexChildCross-Sectional StudiesFemaleHumansMaleMotor ActivityObesity, AbdominalObservational Studies as TopicWaist Circumferenceabdominal adiposityaccelerometrybirth weightmediationsedentary timeyouth

Identifiers

PMID25832337
PMCPMC4409689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.