Trial reportPhysiological measurement2015
A rate-based transcutaneous CO2 sensor for noninvasive respiration monitoring.
Trial report in Physiological measurement, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Towards accurate transcutaneous COBiosensors & bioelectronics · 2026Article
- Room temperature sensing of CORSC advances · 2025Article
- Recent Technologies for Transcutaneous Oxygen and Carbon Dioxide Monitoring.Diagnostics (Basel, Switzerland) · 2024Review
- Physiological effects of N95 respirators on rescuers during cardiopulmonary resuscitation.Heliyon · 2023Article
- Dynamic Modeling of Carbon Dioxide Transport through the Skin Using a Capnometry Wristband.Sensors (Basel, Switzerland) · 2023Article
- Noninvasive carbon dioxide monitoring in pediatric patients undergoing laparoscopic surgery: transcutaneous vs. end-tidal techniques.BMC pediatrics · 2023Article
- A novel approach to noninvasive monitoring of dissolved carbon dioxide in small-scale cell culture processes.Frontiers in bioengineering and biotechnology · 2022Article
- Carbon Dioxide Sensing-Biomedical Applications to Human Subjects.Sensors (Basel, Switzerland) · 2021Review
- What do masks mask? A study on transdermal COMedical engineering & physics · 2021Article
- Wearable Transcutaneous COIEEE sensors journal · 2021Article
- Wearable Health Devices-Vital Sign Monitoring, Systems and Technologies.Sensors (Basel, Switzerland) · 2018Review
- Development and characterization of a point-of care rate-based transcutaneous respiratory status monitor.Medical engineering & physics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
The pain and risk of infection associated with invasive blood sampling for blood gas measurements necessitate the search for reliable noninvasive techniques. In this work we developed a novel rate-based noninvasive method for a safe and fast assessment of respiratory status. A small sampler was built to collect the gases diffusing out of the skin. It was connected to a CO2 sensor through gas-impermeable tubing. During a measurement, the CO2 initially present in the sampler was first removed by purging it with nitrogen. The gases in the system were then recirculated between the sampler and the CO2 sensor, and the CO2 diffusion rate into the sampler was measured. Because the measurement is based on the initial transcutaneous diffusion rate, reaching mass transfer equilibrium and heating the skin is no longer required, thus, making it much faster and safer than traditional method. A series of designed experiments were performed to analyze the effect of the measurement parameters such as sampler size, measurement location, subject positions, and movement. After the factor analysis tests, the prototype was sent to a level IV NICU for clinical trial. The results show that the measured initial rate of increase in CO2 partial pressure is linearly correlated with the corresponding arterial blood gas measurements. The new approach can be used as a trending tool, making frequent blood sampling unnecessary for respiratory status monitoring.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.