ArticleProceedings of the National Academy of Sciences of the United States of America2015
Sexual selection drives evolution and rapid turnover of male gene expression.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
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118 citing papers in PubMed, 251 citations in OpenAlex.
- Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches.Genome biology and evolution · 2026Article
- The molecular evolution of vertebrate organs.Nature ecology & evolution · 2026Review
- Conservation and divergence of sex-biased gene expression across 50 million years of Drosophila evolution.Molecular biology and evolution · 2026Article
- Organization and evolution of sex-biased gene expression inbioRxiv : the preprint server for biology · 2026Article
- Rapid promoter evolution of male accessory gland genes is accompanied by divergent expression in closely related Drosophila species.Genetics · 2025Article
- Sex-biased duplicates are rapidly generated duringbioRxiv : the preprint server for biology · 2025Article
- Structural and evolutionary features of red algal UV sex chromosomes.Genome biology · 2025Article
- Comparative Genomics of Sex-Determination-Related Genes Reveals Shared Evolutionary Patterns Between Bivalves and Mammals, but Not Fruit Flies.Molecular ecology · 2025Article
- Evolution of Sex-Biased Gene Expression During Transitions to Separate Sexes in the Silene Genus.Molecular biology and evolution · 2025Article
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- Evolutionary Analysis of Sex-Biased Gene Suggests Functional Conservation of Lifespan-Related Genes in Insecta.Biology · 2025Article
- Sexual Selection on Non-Ornamental Traits Is Underpinned by Evidence of Genetic Constraints on Sex-Biased Expression in Dusky Pipefish.Molecular ecology · 2025Article
- Sex-Biased Gene Expression Under Sexually Antagonistic and Sex-Limited Selection.Molecular biology and evolution · 2025Article
- Sex-biased expression of sex-linked transcripts in spiny frogs with homomorphic sex chromosomes.BMC genomics · 2025Article
- Faster adaptation but slower divergence of X chromosomes under paternal genome elimination.Nature communications · 2025Article
- Natural Variation in Sexual Traits and Gene Expression between Selfing and Outcrossing Arabidopsis lyrata Suggests Sexual Selection at Work.Plant & cell physiology · 2025Article
- Blue light restores functional circadian clocks in eyeless cave spiders.Science advances · 2025Article
- Article
- Sharp decline in male fertility in F2 hybrids of the female-heterogametic silk moth Bombyx.Genetics · 2024Article
- The male and female genomes of golden pompano (Trachinotus ovatus) provide insights into the sex chromosome evolution and rapid growth.Journal of advanced research · 2024Article
58 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
The profound and pervasive differences in gene expression observed between males and females, and the unique evolutionary properties of these genes in many species, have led to the widespread assumption that they are the product of sexual selection and sexual conflict. However, we still lack a clear understanding of the connection between sexual selection and transcriptional dimorphism, often termed sex-biased gene expression. Moreover, the relative contribution of sexual selection vs. drift in shaping broad patterns of expression, divergence, and polymorphism remains unknown. To assess the role of sexual selection in shaping these patterns, we assembled transcriptomes from an avian clade representing the full range of sexual dimorphism and sexual selection. We use these species to test the links between sexual selection and sex-biased gene expression evolution in a comparative framework. Through ancestral reconstruction of sex bias, we demonstrate a rapid turnover of sex bias across this clade driven by sexual selection and show it to be primarily the result of expression changes in males. We use phylogenetically controlled comparative methods to demonstrate that phenotypic measures of sexual selection predict the proportion of male-biased but not female-biased gene expression. Although male-biased genes show elevated rates of coding sequence evolution, consistent with previous reports in a range of taxa, there is no association between sexual selection and rates of coding sequence evolution, suggesting that expression changes may be more important than coding sequence in sexual selection. Taken together, our results highlight the power of sexual selection to act on gene expression differences and shape genome evolution.
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