ArticlePloS one2015
The volume ratio of ground glass opacity in early lung CT predicts mortality in acute paraquat poisoning.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Sequential organ failure assessment in predicting mortality after paraquat poisoning: A meta-analysis.PloS one · 2018Pooled it
- Pooled it
- Indian Society of Critical Care Medicine Position Statement on the Management of Paraquat Poisoning.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Complete pulmonary and renal recovery following severe paraquat poisoning: a six‑month radiological follow‑up and dynamic hematological observation.International journal of emergency medicine · 2026Article
- Utility of Clinical Variables for Deciding Palliative Care in Paraquat Poisoning: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Prognostic Value of the Average Lung CT Number in Patients with Acute Paraquat Poisoning.Emergency medicine international · 2023Article
- Article
- Development and Validation of a Radiomics Nomogram for Prognosis Prediction of Patients with Acute Paraquat Poisoning: A Retrospective Cohort Study.BioMed research international · 2021Article
- Hyperamylasemia as an early predictor of mortality in patients with acute paraquat poisoning.The Journal of international medical research · 2020Article
- Does hemoperfusion in combination with other treatments reduce the mortality of patients with paraquat poisoning more than hemoperfusion alone: A systematic review with meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Ratio of Injured Lung Volume Fraction in Prognosis Evaluation of Acute PQ Poisoning.BioMed research international · 2018Article
- Point-of-care testing in the early diagnosis of acute pesticide intoxication: The example of paraquat.Biomicrofluidics · 2018Review
- Hyperamylasemia as an Early Predictor of Mortality in Patients with Acute Paraquat Poisoning.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Paraquat Poisoning in Patients With HIV Infection: A Case Report and Literature Review.Medicine · 2016Review
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary injury is the main cause of death in acute paraquat (PQ) poisoning. However, whether quantitative lung computed tomography (CT) can be useful in predicting the outcome of PQ poisoning remains unknown. We aimed to identify early findings of quantitative lung CT as predictors of outcome in acute PQ poisoning.
methodsLung CT scanning (64-slide) and quantitative CT lesions were prospectively measured for patients after PQ intoxication within 5 days. The study outcome was mortality during 90 days follow-up. Survival curves were derived by the Kaplan-Meier method, and mortality risk factors were analyzed by the forward stepwise Cox regression analysis.
resultsOf 97 patients, 41 (42.3%) died. Among the eight different types of lung CT findings which appeared in the first 5-day of PQ intoxication, four ones discriminated between survivors and non-survivors including ground glass opacity (GGO), consolidation, pneumomediastinum and "no obvious lesion". With a cutoff value of 10.8%, sensitivity of 85.4% and specificity of 89.3%, GGO volume ratio is better than adopted outcome indicators in predicting mortality, such as estimated amount of PQ ingestion, plasma or urine PQ concentration, acute physiology and chronic health evaluation (APACHE) II and sequential organ failure assessment (SOFA) scores. GGO volume ratios above 10.8% were associated with increased mortality (hazard ratio, 5.82; 95% confidence interval, 4.77-7.09; P < 0.001).
conclusionsThe volume ratio of GGO exceeding 10.8% is a novel, reliable and independent predictors of outcome in acute PQ poisoning.
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