Evidence map›Paper›PMID 25830117›Full record

ArticleAnesthesiology and pain medicine2015

The effect of magnesium sulfate on motor and sensory axillary plexus blockade.

Mohammad Haghighi, Mehran Soleymanha, Abbas Sedighinejad, Ahmadreza Mirbolook, Bahram Naderi Nabi, Mehdi Rahmati, Nasim Ashoori Saheli

Open access · hybridAbstract read
In one paragraph

Article in Anesthesiology and pain medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohammad HaghighiAnesthesiology Research Centre, Guilan University of Medical Sciences, Rasht, Iran.
Mehran SoleymanhaOrthopedic Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Abbas SedighinejadAnesthesiology Research Centre, Guilan University of Medical Sciences, Rasht, Iran.
Ahmadreza MirbolookOrthopedic Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Bahram Naderi NabiAnesthesiology Research Centre, Guilan University of Medical Sciences, Rasht, Iran.
Mehdi RahmatiAnesthesiology Department, Intensive Care Unit Ward , Erfan Private Hospital, Rasht, Iran.
Nasim Ashoori SaheliAnesthesiology Research Centre, Guilan University of Medical Sciences, Rasht, Iran.
Guilan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnesium is a physiologic cation that blocks neuromuscular transmission and does not allow the nerve to be stimulated.

objectivesThis study investigates the effect of adding magnesium sulfate to lidocaine to extend the duration of sensory and motor blocks of the axillary plexus in orthopedic surgeries of the upper extremities. PATIENTS AND

methodsThis controlled randomized double-blind study was performed on patients who were candidates for orthopedic surgery of the upper extremities. A total of 60 patients between 18-60 years with ASA Class 1 or 2 participated in the study. One group received lidocaine (5 mg/kg) with magnesium sulfate 20% (3 mL) as the case group, while the second group received lidocaine (5 mg/kg) with normal saline (3 mL) as a placebo to block the axillary plexus using the trans-arterial technique. The duration of the sensory and motor block of the axillary plexus was monitored and evaluated using the pinprick and modified Bromage scale.

resultsA total of 60 patients were included in the study with 30 patients having received lidocaine plus magnesium and the other 30 patients having received lidocaine plus normal saline. The mean sensory block duration in the case group was 248.83 ± 18.36 and in control group was 204.67 ± 22.62. The mean motor block duration in the case group was 207.0 ± 16.64 and in control group was 147.33 ± 21.52 (both P < 0.0001). The mean onset of sensory block in case group was 15.5 ± 3.79 and the onset block in control group was 10.33 ± 4.13 (P < 0.0001). The mean onset of motor block in case group was 20.66 ± 4.09 and the onset block in control group was 19.73 ± 26.18 (P < 0.848).

conclusionsThe addition of magnesium sulfate to lidocaine increased the duration of motor and sensory axillary block in the upper extremities during surgeries when compared to the use of lidocaine alone.

Indexed as

LidocaineMagnesium SulfateRegional anesthesia

Identifiers

PMID25830117
PMCPMC4363737
OpenAlexW2096953442

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.