Evidence map›Paper›PMID 25830036›Full record

ArticleJournal of gastrointestinal oncology2015

Low bone mineral density linked to colorectal adenomas: a cross-sectional study of a racially diverse population.

Shilpa Gowda, Seth Lipka, Ashley H Davis-Yadley, Huafeng Shen, Jeffrey Silpe, Andy White, Sam Satler, Dustin Luebbers, James Statler, Anna Zheng and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Shilpa Gowda1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Seth Lipka1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Ashley H Davis-Yadley1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Huafeng Shen1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Jeffrey Silpe1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Andy White1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Sam Satler1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Dustin Luebbers1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
James Statler1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Anna Zheng1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Joshua Elder1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Albin Abraham1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Prakash Viswanathan1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Paul Mustacchia1 Division of Occupational and Environmental Health Sciences, University of Washington School of Medicine and University of Washington School of Public Health, Seattle, WA, USA ; 2 Division of Digestive Diseases and Nutrition, 3 Department of Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 4 Department of Medicine, 5 Division of Gastroenterology and Hepatology, Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA.
University of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiologic studies suggest that lower bone mineral density (BMD) is associated with an increased risk for colorectal adenoma/cancer, especially in postmenopausal women. The aim of this study is to investigate the association between osteopenia and/or osteoporosis and colorectal adenomas in patients from a New York community hospital.

methodsWe performed a cross-sectional observational study on 200 patients who underwent screening colonoscopies and bone density scan (dual-energy X-ray absorptiometry) at Nassau University Medical Center from November 2009 to March 2011. Among these, 83 patients were identified as osteoporosis (T score of -2.5 or below) and 67 were osteopenia (T score between -1.0 and -2.5). Logistic regression model was performed to assess the association between osteopenia and/or osteoporosis and colorectal adenomas.

resultsAmong the patients with osteopenia and osteoporosis, the mean ages were 59.1 years [standard deviation (SD) =8.9] and 61.5 (SD =8.9), respectively. There were 94.0%, 85.1% and 74.7% women, respectively, in normal BMD, osteopenia and osteoporosis groups. The prevalence of colorectal adenomas was 17.9% and 25.3% in the osteopenia and osteoporosis groups, respectively, and 18.0% in the normal BMD group. After adjustment for potential confounders including age, sex, race, body mass index (BMI), tobacco use, alcohol use, history of diabetes, hypertension, or dyslipidemia, osteoporosis was found to be associated with presence of colorectal adenomas more than 2, compared to the normal BMD group. No significant associations were found for the prevalence, size, and location of adenomas.

conclusionsOur study suggests that osteoporosis is significantly associated with the presence of multiple colorectal adenomas. Prospective studies with a larger sample size are warranted in the future.

Indexed as

Bone mineral density (BMD)colonoscopycolorectal adenomaosteoporosis

Identifiers

PMID25830036
PMCPMC4311102
OpenAlexW167329744

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.