ArticleSaudi journal of anaesthesia
The safety of ultrasound guided central venous cannulation in patients with liver disease.
Article in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02987712 (Management of Coagulopathy in Cirrhotic Patients Undergoing Invasive Procedures), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management of Coagulopathy in Cirrhotic Patients Undergoing Invasive Procedures: a Prospective Trial Comparing Standard Management to Thromboelastography Protocol Based Management
Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Rotational thromboelastometry helped reduce prophylactic blood product use for port insertion in patients with liver failure undergoing plasma exchange.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Article
- Rethinking pre-procedural coagulation management in acute liver failure and acute-on-chronic liver failure: The emerging role of rotational thromboelastometry.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Article
- External Guidewire Direction as an Adjunctive Clue for Accurate Central Venous Catheter Placement: A Case Report.Cureus · 2025Article
- Minimum platelet count threshold before invasive procedures in cirrhosis: Evolution of the guidelines.World journal of gastrointestinal surgery · 2023Review
- Central venous catheterization in cancer patients with severe thrombocytopenia: Ultrasound-guide improves safety avoiding prophylactic platelet transfusion.Molecular and clinical oncology · 2020Article
- Clinical Implications of Thrombocytopenia for the Cirrhotic Patient.Hepatic medicine : evidence and research · 2020Review
- Recommendations on the Use of Ultrasound Guidance for Central and Peripheral Vascular Access in Adults: A Position Statement of the Society of Hospital Medicine.Journal of hospital medicine · 2019Article
- Article
- Perioperative Care of Patients With Liver Cirrhosis: A Review.Health services insights · 2017Review
- Inserting central venous catheter in emergency conditions in coagulopathic patients in comparison to noncoagulopathic patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCentral venous cannulation (CVC) is frequently required during the management of patients with liver disease with deranged conventional coagulation parameters (CCP). Since CVC is known to be associated with vascular complications, it is standard practice to transfuse Fresh-Frozen Plasma or platelets to correct CCP. These CCP may not reflect true coagulopathy in liver disease. Additionally CVC when performed under ultrasound guidance (USG-CVC) in itself reduces the incidence of complications.
aimTo assess the safety of USG-CVC and to evaluate the incidence of complications among liver disease patients with coagulopathy. SETTING AND
designAn audit of all USG-CVCs was performed among adult patients with liver disease in a tertiary care center. MATERIALS AND
methodsData was collected for all the adult patients (18-60 years) of either gender suffering from liver disease who had required USG-CVC. Univariate and multivariate regression analysis was done to identify possible risk factors for complications.
resultsThe mean age of the patients was 42.1 ± 11.6 years. Mean international normalized ratio was 2.17 ± 1.16 whereas median platelet count was 149.5 (range, 12-683) × 10(9)/L. No major vascular or non-vascular complications were recorded in our patients. Overall incidence of minor vascular complications was 18.6%, of which 13% had significant ooze, 10.3% had hematoma formation and 4.7% had both hematoma and ooze. Arterial puncture and multiple attempts were independent risk factors for superficial hematoma formation whereas low platelet count and presence of ascites were independent risk factors for significant oozing.
conclusionUltrasound guidance -CVC in liver disease patients with deranged coagulation is a safe and highly successful modality.
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