Trial reportArchives of disease in childhood2015
Using digital multimedia to improve parents' and children's understanding of clinical trials.
Trial report in Archives of disease in childhood, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Do studies of interventions to improve laypeople's critical thinking about health choices assess potential harms? A systematic review.BMJ open · 2026Pooled it
- Can we achieve better trial recruitment by presenting patient information through multimedia? Meta-analysis of 'studies within a trial' (SWATs).BMC medicine · 2023Pooled it
- Improving assent in health research: a rapid systematic review.BMC medical research methodology · 2020Pooled it
- Educational interventions to improve people's understanding of key concepts in assessing the effects of health interventions: a systematic review.Systematic reviews · 2018Pooled it
- Digital animation as a tool to enhance informed consent when recruiting infants with biliary atresia to a clinical trial.Journal of pediatric gastroenterology and nutrition · 2025Trial
- Trial
- Journal of child health care : for professionals working with children in the hospital and community · 2022Trial
- Evaluating the use of multimedia information when recruiting adolescents to orthodontics research: A randomised controlled trial.Journal of orthodontics · 2021Trial
- Improving quality of the informed consent process: Developing an easy-to-read, multimodal, patient-centered format in a real-world setting.Patient education and counseling · 2019Trial
- Trial
- Evaluation of an Interactive, Educational Website Developed for Adolescents to Learn About Pediatric Clinical Trials: DigiKnowIt News.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & PractitionersTrial
- AI-assisted consent in paediatric medicine: ethical implications of using large language models to support decision-making.Journal of medical ethics · 2026Article
- Digital informed consent for paediatric spinal surgery: a patient-centric evaluation of eConsent utilization.Journal of spine surgery (Hong Kong) · 2026Article
- Animated videos for childhood cancer precision medicine: development and evaluation with parents and patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Using dataflow diagrams to support research informed consent data management communications: participant perspectives.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- AI meets informed consent: a new era for clinical trial communication.JNCI cancer spectrum · 2025Article
- Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study.Trials · 2025Article
- Enhancing informed consent through multimedia tools in pediatric spinal surgery: a comprehensive review.Frontiers in pediatrics · 2024Review
- Article
- Comprehension by Caregivers and Adolescents of Clinical Trial Information Delivered via Multimedia Video Versus Conventional Practice: Nonrandomized Controlled Trial.JMIR pediatrics and parenting · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectiveData show that many research subjects have difficulty understanding study information using traditional paper consent documents. This study, therefore, was designed to evaluate the effect of an interactive multimedia program on improving parents' and children's understanding of clinical trial concepts and participation.
methodsParents (n=148) and children (n=135) were each randomised to receive information regarding clinical trials using either a traditional paper format (TF) or an interactive iPad program (IP) with inline exercises. Participants' understanding of the information was assessed using semistructured interviews prior to (pretest) and after (post-test) receiving the information. Participants also completed a short survey to assess their perceptions of information delivery and satisfaction with the process.
resultsRegardless of the mode of information delivery, all participants demonstrated improved pretest to post-test understanding. While there were no statistical differences in parents' post-test understanding between the TF and IP groups, children in the IP group had significantly greater post-test understanding compared with children in the TF group (11.65 (4.1) vs 8.85 (4.1) (2.8, 1.4, 4.2) 0-18 scale where 18=complete understanding). Furthermore, the IP was found to be significantly 'easier to follow' and 'more effective' in presenting information compared with the TF.
conclusionsResults demonstrated the importance of providing information regarding clinical trial concepts to parents and children. Importantly, the ability of interactive multimedia to improve understanding of clinical trial concepts and satisfaction with information delivery, particularly among children, supports this approach as a novel and effective vehicle for enhancing the informed consent process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.