Evidence map›Paper›PMID 25829236›Full record

ReviewPsychosomatic medicine2015

Cardiovascular recovery from psychological and physiological challenge and risk for adverse cardiovascular outcomes and all-cause mortality.

Vanessa Panaite, Kristen Salomon, Alvin Jin, Jonathan Rottenberg

Abstract readReview
In one paragraph

Review in Psychosomatic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Purpose in Life and Stress Reactivity.Methods in molecular biology (Clifton, N.J.) · 2025
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  9. Review
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  11. Advancing the Study of Resilience to Daily Stressors.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Vanessa PanaiteFrom the Department of Psychology, University of South Florida, Tampa, Florida.
Kristen Salomon
Alvin Jin
Jonathan Rottenberg

Funding

Vagal fluctuation as a predictor of current and future depressionR21MH077669 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI ROTTENBERG, JONATHAN ADAM · 2008 to 2009
$363k
NIMH NIH HHS MH077669-02NIMH NIH HHS R21 MH077669
6 · The paper itself

Abstract

objectiveExaggerated cardiovascular (CV) reactivity to laboratory challenge has been shown to predict future CV morbidity and mortality. CV recovery has been less studied and has yielded inconsistent findings, possibly due to the presence of moderators. Reviews on the relationship between CV recovery and CV outcomes have been limited to cross-sectional studies and have not considered methodological factors. We performed a comprehensive meta-analytic review of the prospective literature investigating CV recovery to physical and psychological challenge and adverse CV outcomes.

methodsWe searched PsycINFO and PubMed for prospective studies investigating the relationship between CV recovery and adverse CV outcomes. Studies were coded for variables of interest and for effect sizes. We conducted a random-effects weighted meta-analysis. Moderators were examined with analysis of variance-analog and meta-regression analyses.

resultsThirty-seven studies met the inclusion criteria (n = 125,386). Impaired recovery from a challenge predicted adverse CV outcomes (summary effect, r = 0.17, p < .001). Physical challenge was associated with larger predictive effects than psychological challenge. Moderator analyses revealed that recovery measured at 1 minute postexercise, passive recovery, use of mortality as an outcome measure, and older sample age were associated with larger effects.

conclusionsPoor recovery from laboratory challenges predicts adverse CV outcomes, with recovery from exercise serving as a particularly strong predictor of CV outcomes. The overall effect size for recovery and CV outcomes is similar to that observed for CV reactivity and suggests that the study of recovery may have incremental value for understanding adverse CV outcomes.

Indexed as

Cardiovascular DiseasesCardiovascular SystemHumansMortalityProspective StudiesRecovery of FunctionRegression AnalysisStress, PhysiologicalStress, Psychological

Identifiers

PMID25829236
PMCPMC4397577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.