SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2015
Health-related quality of life among children, young people and adults with esophageal atresia: a review of the literature and recommendations for future research.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- The International Network on Oesophageal Atresia (INoEA) consensus guidelines on the transition of patients with oesophageal atresia-tracheoesophageal fistula.Nature reviews. Gastroenterology & hepatology · 2023Guideline
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Health-related quality of life in adults with epidermolysis bullosa: a cross-sectional study in seven European countries using EQ-5D-5L.Orphanet journal of rare diseases · 2026Article
- Parents' experiences of condition management in children born with esophageal atresia-tracheoesophageal fistula during their early childhood.Orphanet journal of rare diseases · 2026Article
- Disease-specific quality of life after thoracoscopic repair of esophageal atresia: a single-centre cross-sectional study.Frontiers in pediatrics · 2026Article
- Does thoracoscopic repair of type C esophageal atresia require emergency treatment?BMC surgery · 2025Article
- Disease-specific quality of life as part of the long-term follow-up for children born with esophageal atresia in an academic unit in South Africa-a pilot study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- An International Collaborative Initiative to Establish a Quality-of-Life Questionnaire for Children and Adolescents with Repair of Esophageal Atresia in 14 Countries.Children (Basel, Switzerland) · 2024Article
- Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors.Children (Basel, Switzerland) · 2023Article
- Health-related quality of life and patient-reported outcome measurements in patients with cystinosis.JIMD reports · 2023Article
- Establishment of a condition-specific quality-of-life questionnaire for children born with esophageal atresia aged 2-7 across 14 countries.Frontiers in pediatrics · 2023Article
- Health-related quality of life in children after surgical repair of esophageal atresia: a cross-sectional study in China.Frontiers in pediatrics · 2023Article
- Long-term outcomes in newborn surgery.Pediatric surgery international · 2022Review
- The Chinese Mandarin Version of the Esophageal-Atresia-Quality-of-Life Questionnaires for Children and Adolescents: Evaluation of Linguistic and Content Validity.International journal of environmental research and public health · 2022Article
- Feasibility, Reliability, and Validity of the Turkish Version of the Esophageal-Atresia-Quality-of-Life Questionnaires to Assess Condition-Specific Quality of Life in Children and Adolescents Born with Esophageal Atresia.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- Children and adolescents with VACTERL association: health-related quality of life and psychological well-being in children and adolescents and their parents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Agreement between mothers', fathers', and children's' ratings on health-related quality of life in children born with esophageal atresia - a German cross-sectional study.BMC pediatrics · 2019Article
- Changes in quality of life from infancy to school age after esophagoesophagostomy for tracheoesophageal fistula: thoracotomy versus thoracoscopy.Pediatric surgery international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEsophageal atresia (EA) is a rare congenital malformation requisite of surgical treatment. Survival rates have significantly increased in recent decades, but treated children are at risk of chronic morbidity. This study aims to review the literature on health-related quality of life (HRQOL) in patients with EA and describe the questionnaires used.
methodsA literature search was conducted in Pubmed, Cinahl and PsycINFO, from inception to January 2015. A meta-analysis of studies investigating HRQOL in patients with EA compared to healthy references was performed. The effect size was calculated as Cohen's d.
resultsTwelve articles (published 1995-2014) describing HRQOL among children, young people and adults were identified. Only European studies were found, and these had variable sample sizes (8-128). Overall HRQOL was reported to be reduced in five of the seven studies that compared overall HRQOL with a healthy reference population. Impaired physical or general health was described in eight articles. In the meta-analysis, eight eligible studies provided 16 estimates of the effect of EA, six of which reached statistical significance for worse HRQOL (p < 0.05). Using Cohen's criteria, the pooled estimate of the effect of EA was small for overall and physical HRQOL, and <0.2 for the mental and social HRQOL components. Altogether, 15 different questionnaires were used, and none were condition specific for EA.
conclusionsDifferent findings are reported; however, this study suggests that patients with EA may have a reduced HRQOL. Moreover, HRQOL is not adequately measured in this group. Additional research is required.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.