ArticleJournal of pain and symptom management2015
Predictors and Trajectories of Morning Fatigue Are Distinct From Evening Fatigue.
Article in Journal of pain and symptom management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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Who cites it
44 citing papers in PubMed.
- Central nervous system symptom burden and clinical implications for antiemetic management with olanzapine in AC chemotherapy.The oncologist · 2026Trial
- Evaluation of coping as a mediator of the relationship between stressful life events and cancer-related distress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017Trial
- Joint nausea and fatigue profiles during chemotherapy identify patients with a higher symptom burden.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Distinct Morning and Evening Fatigue Profiles in Patients With Gynecologic Cancers Receiving Chemotherapy.Oncology nursing forum · 2025Article
- Prevalence and biopsychosocial indicators of fatigue in cancer patients.Cancer medicine · 2024Article
- Distinct morning and evening fatigue profiles in gastrointestinal cancer during chemotherapy.BMJ supportive & palliative care · 2023Article
- Validation of a short version of the Lee fatigue scale in adults living in Norway: a cross-sectional population survey.BMC public health · 2023Article
- Beyond the symptom: the biology of fatigue.Sleep · 2023Review
- Identification of distinct symptom profiles in patients with gynecologic cancers using a pre-specified symptom cluster.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Prediction of morning fatigue severity in outpatients receiving chemotherapy: less may still be more.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Higher Stress in Oncology Patients is Associated With Cognitive and Evening Physical Fatigue Severity.Journal of pain and symptom management · 2023Article
- Impact of worst pain severity and morning fatigue profiles on oncology outpatients' symptom burden and quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Cumulative burden of symptomatology in patients with gynecologic malignancies undergoing chemotherapy.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022Article
- Fatigue as a complicating factor in the recovery of breast cancer survivors treated at an oncology clinic in South West Nigeria: a case-control study.Ecancermedicalscience · 2022Article
- Subgroups of patients undergoing chemotherapy with distinct cognitive fatigue and evening physical fatigue profiles.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Distinct diarrhea profiles during outpatient chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Perturbations in Endocytotic and Apoptotic Pathways Are Associated With Chemotherapy-Induced Nausea.Biological research for nursing · 2021Article
- Prediction of evening fatigue severity in outpatients receiving chemotherapy: less may be more.Fatigue : biomedicine, health & behavior · 2021Article
- Gastrointestinal symptoms are associated with trajectories of chemotherapy-induced nausea.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Neuropsychological Symptoms and Intrusive Thoughts Are Associated With Worse Trajectories of Chemotherapy-Induced Nausea.Journal of pain and symptom management · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
contextFatigue is the most common symptom in oncology patients during chemotherapy. Little is known about the predictors of interindividual variability in initial levels and trajectories of morning fatigue severity in these patients.
objectivesAn evaluation was done to determine which demographic, clinical, and symptom characteristics were associated with initial levels as well as the trajectories of morning fatigue and to compare findings with our companion paper on evening fatigue.
methodsA sample of outpatients with breast, gastrointestinal, gynecological, and lung cancer (n = 586) completed demographic and symptom questionnaires a total of six times over two cycles of chemotherapy. Fatigue severity was evaluated using the Lee Fatigue Scale. Hierarchical linear modeling was used to answer the study objectives.
resultsA large amount of interindividual variability was found in the morning fatigue trajectories. A piecewise model fit the data best. Patients with higher body mass index, who did not exercise regularly, with a lower functional status, and who had higher levels of state anxiety, sleep disturbance, and depressive symptoms reported higher levels of morning fatigue at enrollment. Variations in the trajectories of morning fatigue were predicted by the patients' ethnicity and younger age.
conclusionThe modifiable risk factors that were associated with only morning fatigue were body mass index, exercise, and state anxiety. Modifiable risk factors that were associated with both morning and evening fatigue included functional status, depressive symptoms, and sleep disturbance. Using this information, clinicians can identify patients at higher risk for more severe morning fatigue and evening fatigue, provide individualized patient education, and tailor interventions to address the modifiable risk factors.
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