Evidence map›Paper›PMID 25828100›Full record

GuidelineNeurogastroenterology and motility2015

ANMS-ESNM position paper and consensus guidelines on biofeedback therapy for anorectal disorders.

S S C Rao, M A Benninga, A E Bharucha, G Chiarioni, C Di Lorenzo, W E Whitehead

Registry-linked trialOpen access · greenAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Neurogastroenterology and motility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07705542 (Analysing the Impact of Balloon Inflated vs Balloon Deflated Push Manoeuvres in Chronically Constipated Patients During Biofeedback Therapy), which is not on this map. Cited by 103 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 7 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07705542 narecruitingnot on this mapstarted 2026, after this paper: background citation

Analysing the Impact of Balloon Inflated vs Balloon Deflated Push Manoeuvres in Chronically Constipated Patients During Biofeedback Therapy

TypeinterventionalSponsorHull University Teaching Hospitals NHS TrustRan2026 to 2026Enrolled10ConditionsConstipation, Chronic Constipation, Dyssynergia, AnismusArmsInflating anorectal catheter balloon to defecatory desired volume during push manoeuvres in biofeedback therapy., No intervention
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 7 syntheses or guidelines pooled it, 250 citations in OpenAlex.

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  20. Research priorities for faecal incontinence in adults: A James Lind Alliance priority setting partnership.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

S S C RaoSection of Gastroenterology/Hepatology, Georgia Regents University, Augusta, GA, USA.
M A Benninga
A E Bharucha
G Chiarioni
C Di Lorenzo
W E Whitehead
Augusta University · USEmma Kinderziekenhuis · NLMayo Clinic in Arizona · USNationwide Children's Hospital · USUniversity of North Carolina at Chapel Hill · USUniversity of Verona · IT

Funding

Pathophysiology of Anorectal DisordersR01DK078924 · NIDDK · MAYO CLINIC ROCHESTER · PI BHARUCHA, ADIL E. · 2008 to 2023
$5.0M
Novel Treatment Strategies for Constipation and Role of Brain-Gut axisR01DK057100 · NIDDK · UNIVERSITY OF IOWA · PI RAO, SATISH SC · 2000 to 2011
$2.7M
Conservative Treatment of Fecal Incontinence in the Elderly: Effectiveness TR01HS018695 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 2012 to 2014
$1.4M
Website for Self-Management of Fecal IncontinenceR21DK096545 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 2013 to 2014
$418k
AHRQ HHS R01 HS018695AHRQ HHS R01HS018695NIDDK NIH HHS R01 DK057100NIDDK NIH HHS R01 DK078924NIDDK NIH HHS R01DK57100-03NIDDK NIH HHS R01DK78924NIDDK NIH HHS R21 DK096545NIDDK NIH HHS R21DK096545
6 · The paper itself

Abstract

backgroundAnorectal disorders such as dyssynergic defecation, fecal incontinence, levator ani syndrome, and solitary rectal ulcer syndrome are common, and affect both the adult and pediatric populations. Although they are treated with several treatment approaches, over the last two decades, biofeedback therapy using visual and verbal feedback techniques has emerged as an useful option. Because it is safe, it is commonly recommended. However, the clinical efficacy of biofeedback therapy in adults and children is not clearly known, and there is a lack of critical appraisal of the techniques used and the outcomes of biofeedback therapy for these disorders. PURPOSE: The American Neurogastroenterology and Motility Society and the European Society of Neurogastroenterology and Motility convened a task force to examine the indications, study performance characteristics, methodologies used, and the efficacy of biofeedback therapy, and to provide evidence-based recommendations. Based on the strength of evidence, biofeedback therapy is recommended for the short-term and long-term treatment of constipation with dyssynergic defecation (Level I, Grade A), and for the treatment of fecal incontinence (Level II, Grade B). Biofeedback therapy may be useful in the short-term treatment of Levator Ani Syndrome with dyssynergic defecation (Level II, Grade B), and solitary rectal ulcer syndrome with dyssynergic defecation (Level III, Grade C), but the evidence is fair. Evidence does not support the use of biofeedback for the treatment of childhood constipation (Level 1, Grade D).

Indexed as

AdultAnus DiseasesBiofeedback, PsychologyChildConstipationElectromyographyEuropeFecal IncontinenceGastroenterologyHumansManometryPainRectal DiseasesSocieties, MedicalTreatment OutcomeUlcerbiofeedback therapyconstipationdyssynergic defecationfecal incontinencelevator ani syndrome

Identifiers

PMID25828100
PMCPMC4409469
OpenAlexW2093208887

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.