Evidence map›Paper›PMID 25827511›Full record

ArticleInternal medicine journal2015

Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective.

J A Tye-Din, D J S Cameron, A J Daveson, A S Day, P Dellsperger, C Hogan, E D Newnham, S J Shepherd, R H Steele, L Wienholt and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. An Overview of Celiac Disease in Childhood Type 1 Diabetes.International journal of endocrinology and metabolism · 2018
    Review
  11. Testing for coeliac disease.Australian prescriber · 2017
    Review
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J A Tye-DinImmunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Departments of Medical Biology, The University of Melbourne, Melbourne, Victoria, Australia; Department of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia; Medical Advisory Committee, Coeliac Australia, Melbourne, Victoria, Australia.
D J S Cameron
A J Daveson
A S Day
P Dellsperger
C Hogan
E D Newnham
S J Shepherd
R H Steele
L Wienholt
M D Varney

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past decade has seen human leukocyte antigen (HLA) typing emerge as a remarkably popular test for the diagnostic work-up of coeliac disease with high patient acceptance. Although limited in its positive predictive value for coeliac disease, the strong disease association with specific HLA genes imparts exceptional negative predictive value to HLA typing, enabling a negative result to exclude coeliac disease confidently. In response to mounting evidence that the clinical use and interpretation of HLA typing often deviates from best practice, this article outlines an evidence-based approach to guide clinically appropriate use of HLA typing, and establishes a reporting template for pathology providers to improve communication of results.

Indexed as

AustralasiaCeliac DiseaseGenetic Predisposition to DiseaseHistocompatibility TestingHLA AntigensHumansHLA Antigenscoeliac diseasediagnosticsHLA typing

Identifiers

PMID25827511
PMCPMC4405087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.