Evidence map›Paper›PMID 25825828›Full record

ArticleNutrients2015

Oral cancer malnutrition impacts weight and quality of life.

Nils-Claudius Gellrich, Jörg Handschel, Henrik Holtmann, Gertrud Krüskemper

3 registry-linked trialsOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06219083 recruitingnot on this mapstarted 2020, after this paper: background citation

Study of Nutritional Status and Clinical Outcomes in Patients With Common Malignancies

Typeobservational_patient_registrySponsorXiaoqin LuoRan2020 to 2031Enrolled1,538ConditionsCancer, Chemoradiotherapy, Nutrition, Healthy, Oncology
NCT06726317 nacompletednot on this mapstarted 2018, after this paper: background citation

The Prevalence and Associated Factors of Psychological Distress, and Effectiveness of a 'Life Situation Improving Intervention' Among Oral Cancer Patients Attending Tertiary Care Hospitals in the Colombo District

TypeinterventionalSponsorUniversity of ColomboRan2018 to 2020Enrolled110ConditionsOral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of PatientsArmsEarly palliative care integration
NCT07087561 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Effects and Mechanisms of Short-Term Nutritional Enhancement Combined With Health Education on Clinical Outcomes in Postoperative Patients With Colorectal Cancer: A Multicenter, Open-Label, Randomized Controlled Trial

TypeinterventionalSponsorXiaoqin LuoRan2024 to 2030Enrolled360ConditionsColorectal Cancer (Diagnosis), Malnutrition or Risk of MalnutritionArmsPersonalized Oral Nutritional Supplementation, Personalized Parenteral Nutritional Supplementation, Structured Nutrition-Focused Health Education
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 139 citations in OpenAlex.

  1. Guideline
  2. The effects of dietary advice on malnutrition in Cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  19. Health information-seeking experience in people with head and neck neoplasms undergoing treatment: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Nils-Claudius GellrichDepartment of Cranio-Maxillofacial Surgery, Hannover Medical School, Carl-Neuberg-Street 1, Hannover D-30625, Germany. gellrich.nils-claudius@mh-hannover.de.
Jörg HandschelDepartment for Oral and Maxillofacial Surgery, Heinrich Heine University of Düsseldorf, Moorenstr. 5, D-40225 Düsseldorf, Germany. Handschel@med.uni-duesseldorf.de.
Henrik HoltmannDepartment for Oral and Maxillofacial Surgery, Heinrich Heine University of Düsseldorf, Moorenstr. 5, D-40225 Düsseldorf, Germany. Henrik.Holtmann@med.uni-duesseldorf.de.
Gertrud KrüskemperDepartment of Medical Psychology, Ruhr University of Bochum, Universitätsstr. 150, Building MA 0/145, D-44780 Bochum, Germany. krueskem@uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DEMedizinische Hochschule Hannover · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diet is important for both quality of life (QoL) and survival of patients with oral cancer. Their intake of food is impeded by functional restrictions in chewing and swallowing. In the DÖSAK REHAB STUDY 1652 patients from 38 hospitals within the German-language area of Germany; Austria and Switzerland were examined with regard to functional and psychological variables having an impact on diet. Chewing and swallowing are correlated with mobility of the tongue and the mandible as well as opening of the mouth. Thirty five percent of the patients lost weight; 41% maintained their weight and 24% gained weight. The QoL of patients who were able to maintain their weight and of those who gained weight was significantly better than that of patients who lost weight. A normal diet was important for maintaining weight. Mashed food; liquid food and loss of appetite were closely associated with loss of weight; although it was possible for nutritional counseling and dietary support to be implemented particularly favorably in this respect. Due to problems with eating patients' strength deteriorated; thus restricting activity. Radiotherapy had a negative impact on diet and weight. It influenced sense of taste; dryness of the mouth; swelling and discomfort when ingesting food. Pain and scars in the region of the operation also cause patients to dislike hard; spicy and sour food. Support from a nutritional counselor in implementing a calorie-rich diet remedied this and such support needs to be integrated into patient management. The fact that a poor nutritional status is of such great importance is well-known; but what is often lacking is the systematic implementation of continued professional nutritional counseling over a long period of time; weight control and psycho-social support of the operated patients; particularly those who also have had radiotherapy.

Indexed as

Body WeightQuality of LifeAdultAgedAppetiteAustriaDeglutitionDietDisease ManagementEnergy IntakeFemaleGermanyHumansMaleMalnutritionMastication

Identifiers

PMID25825828
PMCPMC4425137
OpenAlexW1989191425

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.