ArticleProceedings of the National Academy of Sciences of the United States of America2015
Coding of envelopes by correlated but not single-neuron activity requires neural variability.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Type I hair cells of striolar and central zones in vestibular organs are essential for head stability and postural control.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- High-Pass Filtering through Short-Term Synaptic Facilitation Amplifies Low-Frequency Modulation of Bursting Input.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling.PLoS computational biology · 2025Article
- Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations.iScience · 2025Article
- Nonresponsive Neurons Improve Population Coding of Object Location.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Descending pathways increase sensory neural response heterogeneity to facilitate decoding and behavior.iScience · 2023Article
- Population Coding of Natural Electrosensory Stimuli by Midbrain Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neural Synchrony Gives Rise to Amplitude- and Duration-Invariant Encoding Consistent With Perception of Natural Communication Stimuli.Frontiers in neuroscience · 2020Article
- Descending pathways mediate adaptive optimized coding of natural stimuli in weakly electric fish.Science advances · 2019Article
- Vestibular processing during natural self-motion: implications for perception and action.Nature reviews. Neuroscience · 2019Review
- Differentially synchronized spiking enables multiplexed neural coding.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Novel Functions of Feedback in Electrosensory Processing.Frontiers in integrative neuroscience · 2019Article
- Article
- Descending pathways generate perception of and neural responses to weak sensory input.PLoS biology · 2018Article
- Population Coding and Correlated Variability in Electrosensory Pathways.Frontiers in integrative neuroscience · 2018Review
- Differential receptive field organizations give rise to nearly identical neural correlations across three parallel sensory maps in weakly electric fish.PLoS computational biology · 2017Article
- SK channel subtypes enable parallel optimized coding of behaviorally relevant stimulus attributes: A review.Channels (Austin, Tex.) · 2017Review
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- Electrosensory processing in Apteronotus albifrons: implications for general and specific neural coding strategies across wave-type weakly electric fish species.Journal of neurophysiology · 2016Article
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6 authors.
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Abstract
Understanding how the brain processes sensory information is often complicated by the fact that neurons exhibit trial-to-trial variability in their responses to stimuli. Indeed, the role of variability in sensory coding is still highly debated. Here, we examined how variability influences neural responses to naturalistic stimuli consisting of a fast time-varying waveform (i.e., carrier or first order) whose amplitude (i.e., envelope or second order) varies more slowly. Recordings were made from fish electrosensory and monkey vestibular sensory neurons. In both systems, we show that correlated but not single-neuron activity can provide detailed information about second-order stimulus features. Using a simple mathematical model, we made the strong prediction that such correlation-based coding of envelopes requires neural variability. Strikingly, the performance of correlated activity at predicting the envelope was similarly optimally tuned to a nonzero level of variability in both systems, thereby confirming this prediction. Finally, we show that second-order sensory information can only be decoded if one takes into account joint statistics when combining neural activities. Our results thus show that correlated but not single-neural activity can transmit information about the envelope, that such transmission requires neural variability, and that this information can be decoded. We suggest that envelope coding by correlated activity is a general feature of sensory processing that will be found across species and systems.
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