Evidence map›Paper›PMID 25825214›Full record

ArticleThe Journal of allergy and clinical immunology2015

Effect of CYP3A5*3 on asthma control among children treated with inhaled beclomethasone.

Chris Stockmann, Christopher A Reilly, Bernhard Fassl, Roger Gaedigk, Flory Nkoy, Bryan Stone, Jessica K Roberts, Derek A Uchida, J Steven Leeder, Catherine M T Sherwin and 3 more

Open access · bronzeAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Impact of CYP3A5 Polymorphisms on Pediatric Asthma Outcomes.International journal of molecular sciences · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chris StockmannDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah; Department of Pharmacology/Toxicology, University of Utah College of Pharmacy, Salt Lake City, Utah.
Christopher A ReillyDepartment of Pharmacology/Toxicology, University of Utah College of Pharmacy, Salt Lake City, Utah.
Bernhard FasslDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Roger GaedigkDivision of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Hospital, Kansas City, Mo.
Flory NkoyDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Bryan StoneDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Jessica K RobertsDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Derek A UchidaDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
J Steven LeederDivision of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Hospital, Kansas City, Mo.
Catherine M T SherwinDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Michael G SpigarelliDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Garold S YostDepartment of Pharmacology/Toxicology, University of Utah College of Pharmacy, Salt Lake City, Utah.
Robert M WardDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah; Department of Pharmacology/Toxicology, University of Utah College of Pharmacy, Salt Lake City, Utah. Electronic address: Robert.Ward@hsc.utah.edu.
University of Utah · USChildren's Mercy Hospital · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
P450 Metabolism of Glucocorticoids in Lungs of Pediatric AsthmaticsR01HD060559 · NICHD · UNIVERSITY OF UTAH · PI REILLY, CHRISTOPHER A · 2010 to 2014
$2.3M
NCATS NIH HHS UL1 TR001425NCRR NIH HHS 5UL1RR025764-02NCRR NIH HHS UL1 RR025764NICHD NIH HHS R01 HD060559
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideAdministration, InhalationAdolescentAnti-Asthmatic AgentsAryl Hydrocarbon HydroxylasesAsthmaBeclomethasoneChildChild, PreschoolCytochrome P-450 CYP3ADisease ManagementFemaleGene ExpressionHumansMaleTreatment OutcomeAnti-Asthmatic AgentsAryl Hydrocarbon HydroxylasesBeclomethasoneCYP3A4 protein, humanCYP3A5 protein, humanCYP3A7 protein, humanCytochrome P-450 CYP3A

Identifiers

PMID25825214
PMCPMC4530077
OpenAlexW2060247958

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.