ReviewNature reviews. Gastroenterology & hepatology2015
Therapeutic options in oesophageal dysphagia.
Review in Nature reviews. Gastroenterology & hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Gastrointestinal Uses of Botulinum Toxin.Handbook of experimental pharmacology · 2021Trial
- Neuroplasticity Elicited by Modified Pharyngeal Electrical Stimulation: A Pilot Study.Brain sciences · 2023Article
- Is Peroral Endoscopic Myotomy a Potential Therapy for Esophageal Absent Contractility?Surgical laparoscopy, endoscopy & percutaneous techniques · 2020Article
- Esophageal Dysphagia in the Elderly.Current treatment options in gastroenterology · 2019Review
- The Role of Botulinum Toxin Injections for Esophageal Motility Disorders.Current treatment options in gastroenterology · 2018Review
- POEM in the Treatment of Esophageal Disorders.Current treatment options in gastroenterology · 2018Review
- Diabetes and the Esophagus.Current treatment options in gastroenterology · 2017Review
- Peroral endoscopic myotomy (POEM) for treating esophageal motility disorders.Annals of translational medicine · 2017Review
- Management of refractory typical GERD symptoms.Nature reviews. Gastroenterology & hepatology · 2016Review
- Established and Emerging Treatment Options for Functional Heartburn and Chest Pain.Current treatment options in gastroenterology · 2016Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-resolution manometry enables the categorization of patients with oesophageal dysphagia caused by oesophageal motility disorders into diagnostic categories according to the Chicago Classification. This Review provides an overview of the literature concerning treatment options for patients with dysphagia associated with achalasia, hypercontractile disorders and hypocontractility disorders of the oesophagus. In achalasia, pharmacotherapy and botulinum toxin are less effective than pneumatic dilation or surgical Heller myotomy, which had comparable efficacy in the largest controlled trial to date. Peroral endoscopic myotomy is a novel therapeutic modality that is currently being evaluated in controlled trials versus pneumatic dilation or surgical myotomy. A variety of medical treatments have been evaluated in hypermotility disorders, but only botulinum toxin injection yielded favourable results in a single controlled trial. Few studies have addressed the treatment of dysphagia in patients with oesophageal hypomotility. A variety of prokinetic agents have been studied, but there is no evidence of clinically relevant efficacy from controlled trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.