ArticleEvolution; international journal of organic evolution2015
Genome-wide tests for introgression between cactophilic Drosophila implicate a role of inversions during speciation.
Article in Evolution; international journal of organic evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 82 citations in OpenAlex.
- Examining the Role of a Chromosomal Inversion in Accumulating Adaptive and Barrier Loci in a Cold-adapted Insect Species.Genome biology and evolution · 2026Article
- Transposable elements as drivers of genome evolution in Drosophila virilis.Nucleic acids research · 2026Article
- Review
- Comparative Genomics of the Testacea Group of Drosophila Reveals Introgression and Variation in Chromosome Size and Structure.Genome biology and evolution · 2025Article
- Complex Genomic Landscape of Inversion Polymorphism in Europe's Most Destructive Forest Pest.Genome biology and evolution · 2024Article
- Testing the evolutionary theory of inversion polymorphisms in the yellow monkeyflower (Mimulus guttatus).Nature communications · 2024Article
- Fundamental Patterns of Structural Evolution Revealed by Chromosome-Length Genomes of Cactophilic Drosophila.Genome biology and evolution · 2024Article
- Chromosomal Inversions and the Demography of Speciation in Drosophila montana and Drosophila flavomontana.Genome biology and evolution · 2024Article
- Inversions maintain differences between migratory phenotypes of a songbird.Nature communications · 2023Article
- Divergence and introgression among theEvolution letters · 2022Article
- Evolution of assortative mating following selective introgression of pigmentation genes between twoEcology and evolution · 2022Article
- Widespread introgression across a phylogeny of 155 Drosophila genomes.Current biology : CB · 2022Article
- Review
- A phylogenomic study of Steganinae fruit flies (Diptera: Drosophilidae): strong gene tree heterogeneity and evidence for monophyly.BMC evolutionary biology · 2020Article
- Demographic history and genomics of local adaptation in blue tit populations.Evolutionary applications · 2020Article
- Transposable elements inMobile DNA · 2020Review
- Host plant-related genomic differentiation in the European cherry fruit fly, Rhagoletis cerasi.Molecular ecology · 2019Article
- Article
- Disentangling structural genomic and behavioural barriers in a sea of connectivity.Molecular ecology · 2019Article
- How chromosomal rearrangements shape adaptation and speciation: Case studies in Drosophila pseudoobscura and its sibling species Drosophila persimilis.Molecular ecology · 2019Article
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4 authors at 3 institutions in 2 countries.
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Abstract
Models of speciation-with-gene-flow have shown that the reduction in recombination between alternative chromosome arrangements can facilitate the fixation of locally adaptive genes in the face of gene flow and contribute to speciation. However, it has proven frustratingly difficult to show empirically that inversions have reduced gene flow and arose during or shortly after the onset of species divergence rather than represent ancestral polymorphisms. Here, we present an analysis of whole genome data from a pair of cactophilic fruit flies, Drosophila mojavensis and D. arizonae, which are reproductively isolated in the wild and differ by several large inversions on three chromosomes. We found an increase in divergence at rearranged compared to colinear chromosomes. Using the density of divergent sites in short sequence blocks we fit a series of explicit models of species divergence in which gene flow is restricted to an initial period after divergence and may differ between colinear and rearranged parts of the genome. These analyses show that D. mojavensis and D. arizonae have experienced postdivergence gene flow that ceased around 270 KY ago and was significantly reduced in chromosomes with fixed inversions. Moreover, we show that these inversions most likely originated around the time of species divergence which is compatible with theoretical models that posit a role of inversions in speciation with gene flow.
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