ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2015
Cerebral hierarchies: predictive processing, precision and the pulvinar.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.
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Who cites it
161 citing papers in PubMed.
- Effective connectivity changes in LSD-induced altered states of consciousness in humans.Proceedings of the National Academy of Sciences of the United States of America · 2019Trial
- Active inference with reusable state-dependent value profiles.Biological cybernetics · 2026Article
- Human claustrum neurons encode uncertainty and prediction errors during aversive learning.Nature neuroscience · 2026Article
- Perceiving the uncertain: predictive coding and individual differences in the dynamics of multistable perception.Cognitive processing · 2026Review
- Learning regularities in noise engages both neural predictive activity and representational changes.Nature communications · 2026Article
- The primate claustrum as a hub for precision weighting of prediction errors across the cortical hierarchy.PLoS biology · 2026Article
- Non-linear relationships between auditory mismatch responses and the inharmonicity of complex sounds.Scientific reports · 2026Article
- From self-organizing systems to subjective temporal extension.Neuroscience of consciousness · 2026Article
- Pulvinar pathways as skip connections in deep neural networks for vision.Frontiers in neuroimaging · 2026Article
- ESMR: a process framework for calibration dynamics across psychosomatic and psychiatric phenomena.Frontiers in psychiatry · 2026Article
- The phantastic organ: predictive processing in the brain.Frontiers in psychology · 2026Review
- Trust your gut: the neuro-gastroenteric mechanics of prediction and expectation.Frontiers in human neuroscience · 2026Article
- A Bayesian framework for happiness, health, and psychological well-being.Frontiers in psychology · 2026Article
- The active construction of past episodes.Translational neuroscience · 2026Article
- A predictive processing framework for body-oriented trauma intervention: a hypothesis illustrated by Body Connect Therapy.Frontiers in psychology · 2026Article
- Ultra-high field brain MRI for functional neurological disorder: opportunities and challenges.NeuroImage. Clinical · 2026Review
- The pulvinar regulates plasticity in human visual cortex.Science advances · 2025Article
- Inharmonicity enhances brain signals of attentional capture and auditory stream segregation.Communications biology · 2025Article
- Differential modulation of positive and negative prediction errors by stimulus variability in the mouse posterior parietal cortex.Communications biology · 2025Article
- Five Fristonian Formulae.Entropy (Basel, Switzerland) · 2025Article
101 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This paper considers neuronal architectures from a computational perspective and asks what aspects of neuroanatomy and neurophysiology can be disclosed by the nature of neuronal computations? In particular, we extend current formulations of the brain as an organ of inference--based upon hierarchical predictive coding--and consider how these inferences are orchestrated. In other words, what would the brain require to dynamically coordinate and contextualize its message passing to optimize its computational goals? The answer that emerges rests on the delicate (modulatory) gain control of neuronal populations that select and coordinate (prediction error) signals that ascend cortical hierarchies. This is important because it speaks to a hierarchical anatomy of extrinsic (between region) connections that form two distinct classes, namely a class of driving (first-order) connections that are concerned with encoding the content of neuronal representations and a class of modulatory (second-order) connections that establish context-in the form of the salience or precision ascribed to content. We explore the implications of this distinction from a formal perspective (using simulations of feature-ground segregation) and consider the neurobiological substrates of the ensuing precision-engineered dynamics, with a special focus on the pulvinar and attention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.