Evidence map›Paper›PMID 25823827›Full record

ReviewCerebellum (London, England)2016

Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias.

Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee and 7 more

Open access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Cerebellum (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 5 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 5 syntheses or guidelines pooled it, 177 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Review
  7. Review
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  10. Review
  11. Article
  12. Review
  13. Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026
    Review
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 6 countries.

Hiroshi MitomaDepartment of Medical Education, Tokyo Medical University, Tokyo, Japan. mitoma@tokyo-med.ac.jp.
Keya AdhikariDepartment of Haematology, Nil Ratan Sircar Medical College, 138 A J C Bose Road, Kolkata, 700014, West Bengal, India.
Daniel AeschlimannMatrix Biology &Tissue Repair Research Unit, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, Wales, UK.
Partha ChattopadhyayDepartment of General Medicine, College of Medicine & Sagore Dutta Hospital, 578 B T Road, Kamarhati-Kolkata, 700056, West Bengal, India.
Marios HadjivassiliouAcademic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield, UK.
Christiane S HampeSchool of Medicine, University of Washington, 850 Republication, Seattle, WA, 98109, USA.
Jérôme HonnoratUniversity Lyon 1, University Lyon, Rue Guillaume Paradin, 69372, Lyon Cedex 08, France.
Bastien JoubertUniversity Lyon 1, University Lyon, Rue Guillaume Paradin, 69372, Lyon Cedex 08, France.
Shinji KakeiTokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Jongho LeeTokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Mario MantoUnité d'Etude du Mouvement, FNRS, Neurologie ULB-Erasme, 808 Route de Lennik, 1070, Brussels, Belgium.
Akiko MatsunagaDepartment of Neurology, University of Fukui Hospital, Fukui, Japan.
Hidehiro MizusawaNational Center of Neurology and Psychiatry, Tokyo, Japan.
Kazunori NanriDepartment of Neurology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Priya ShanmugarajahAcademic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield, UK.
Makoto YonedaFaculty of Nursing and Social Welfare Sciences, Fukui Prefectural University, Fukui, Japan.
Nobuhiro YukiDepartments of Medicine and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Royal Hallamshire Hospital · GBTokyo Metropolitan Institute of Medical Science · JPCardiff University · GBCentre de Recherche en Neurosciences de Lyon · FRCollege of Medicine & Sagore Dutta Hospital · INFukui Prefectural University · JPHospices Civils de Lyon · FRNational Center of Neurology and Psychiatry · JPNational University of Singapore · SGNil Ratan Sircar Medical College and Hospital · INTokyo Medical University · JPTokyo Medical University Hachioji Medical Center · JPUniversity of Fukui Hospital · JPUniversity of Washington · US

Funding

ISLET CELL MEMBRANE ANTIBODIES IN DIABTESR01DK026190 · NIDDK · UNIVERSITY OF WASHINGTON · PI HAMPE, CHRISTIANE S · 1986 to 2016
$4.9M
NIDDK NIH HHS R01 DK026190
6 · The paper itself

Abstract

In the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. In this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. Immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-GAD antibodies, the cerebellar type of Hashimoto's encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, Miller Fisher syndrome, ataxia associated with systemic lupus erythematosus, and paraneoplastic cerebellar degeneration. Humoral mechanisms, cell-mediated immunity, inflammation, and vascular injuries contribute to the cerebellar deficits in immune-mediated cerebellar ataxias.

Indexed as

AnimalsCerebellar AtaxiaCerebellumEncephalitisGlutensHashimoto DiseaseHumansNeuroimmunomodulationGlutensAnti-GAD antibodiesCerebellar ataxiasGluten ataxiaHashimoto’s encephalopathyMiller Fisher syndromeParaneoplastic cerebellar degenerationPrimary autoimmune cerebellar ataxiaSystemic lupus erythematosus

Identifiers

PMID25823827
PMCPMC4591117
OpenAlexW1966222311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.