Evidence map›Paper›PMID 25823546›Full record

ArticleAngewandte Chemie (International ed. in English)2015

Electrochemical assay to detect influenza viruses and measure drug susceptibility.

Xiaohu Zhang, Abasaheb N Dhawane, Joyce Sweeney, Yun He, Mugdha Vasireddi, Suri S Iyer

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Peptide Amphiphile Mediated Co-assembly for Nanoplasmonic Sensing.Angewandte Chemie (International ed. in English) · 2023
    Article
  5. Device integration of electrochemical biosensors.Nature reviews bioengineering · 2023
    Review
  6. Review
  7. Peptidic Sulfhydryl for Interfacing Nanocrystals and Subsequent Sensing of SARS-CoV-2 Protease.Chemistry of materials : a publication of the American Chemical Society · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaohu Zhang788 Petit Science Center, Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA-30302 (USA).
Abasaheb N Dhawane
Joyce Sweeney
Yun He
Mugdha Vasireddi
Suri S Iyer
Georgia State University · US

Funding

Receptor Mimics for Rapid Detection, Typing, and Susceptibility Testing of InflueR01AI089450 · NIAID · UNIVERSITY OF CINCINNATI · PI IYER, SURI SARANATHAN, WEISS, ALISON A. · 2010 to 2014
$2.2M
NIAID NIH HHS R01 AI089450NIAID NIH HHS R01-AI089450
6 · The paper itself

Abstract

An electrochemical assay has been designed to rapidly diagnose influenza viruses. Exposure of a glucose-bearing substrate to influenza viruses or its enzyme, neuraminidase (NA), releases glucose, which was detected amperometrically. Two methods were used to detect released glucose. First, we used a standard glucose blood meter to detect two viral NAs and three influenza strains. We also demonstrated drug susceptibility of two antivirals, Zanamivir and Oseltamivir, using the assay. Finally, we used disposable test strips to detect nineteen H1N1 and H3N2 influenza strains using this assay in one hour. The limit and range of detection of this first generation assay is 10(2) and 10(2)-10(8) plaque forming units (pfu), respectively. Current user-friendly glucose meters can be repurposed to detect influenza viruses.

Indexed as

Electrochemical TechniquesAntiviral AgentsDrug Resistance, ViralGlucoseInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeOseltamivirZanamivirAntiviral AgentsGlucoseOseltamivirZanamivirbiosensorscarbohydrateselectrochemistryglycosidesinfluenza virus

Identifiers

PMID25823546
PMCPMC5453671
OpenAlexW2138736101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.