Evidence map›Paper›PMID 25823517›Full record

ArticleInternational orthopaedics2015

Predictors of pain and disability outcomes in one thousand, one hundred and eight patients who underwent lumbar discectomy surgery.

Chad E Cook, Paul M Arnold, Peter G Passias, Anthony K Frempong-Boadu, Kristen Radcliff, Robert Isaacs, Association for Collaborative Spine Research (ACSR)

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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  13. Influence of perioperative complication severity on 1- and 2-year outcomes of low back surgery.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Chad E CookDepartment of Orthopaedics, Duke University, 2200 W. Main St., Ste. B230, Durham, NC, USA. chad.cook@duke.edu.
Paul M ArnoldDepartment of Neurosurgery, University of Kansas Medical Center, 3901 Rainbow Blvd, Ms3021, Kansas City, KS, 66160, USA. PARNOLD@kumc.edu.
Peter G PassiasDepartment of Orthopaedic Surgery, NYU School of Medicine, 550 1st Avenue, New York, NY, 10016, USA. panagmd@gmail.com.
Anthony K Frempong-BoaduDepartment of Neurosurgery, Division of Spinal Surgery, New York University - Langone Medical Center, 530 1st Avenue, Skirball Suite 8R, New York, NY, 10016, USA. Anthony.Frempong-Boadu@nyumc.org.
Kristen RadcliffDepartment of Orthopaedic Surgery, Rothman Institute, 2500 English Creek Avenue, Egg Harbor, NJ, 08234, USA. radcliffk@gmail.com.
Robert IsaacsDivision of Neurosurgery, Duke University Medical Center, 200 Trent Drive #11, Durham, NC, 27710, USA. Robert.isaacs@duke.edu.
Association for Collaborative Spine Research (ACSR)
Duke Medical Center · USDuke University Hospital · USNew York University · USNYU Langone Health · USRothman Orthopaedics · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA key component toward improving surgical outcomes is proper patient selection. Improved selection can occur through exploration of prognostic studies that identify variables which are associated with good or poorer outcomes with a specific intervention, such as lumbar discectomy. To date there are no guidelines identifying key prognostic variables that assist surgeons in proper patient selection for lumbar discectomy. The purpose of this study was to identify baseline characteristics that were related to poor or favourable outcomes for patients who undergo lumbar discectomy. In particular, we were interested in prognostic factors that were unique to those commonly reported in the musculoskeletal literature, regardless of intervention type.

methodsThis retrospective study analysed data from 1,108 patients who underwent lumbar discectomy and had one year outcomes for pain and disability. All patient data was part of a multicentre, multi-national spine repository. Ten relatively commonly captured data variables were used as predictors for the study: (1) age, (2) body mass index, (3) gender, (4) previous back surgery history, (5) baseline disability, unique baseline scores for pain for both (6) low back and (7) leg pain, (8) baseline SF-12 Physical Component Summary (PCS) scores, (9) baseline SF-12 Mental Component Summary (MCS) scores, and (10) leg pain greater than back pain. Univariate and multivariate logistic regression analyses were run against one year outcome variables of pain and disability.

resultsFor the multivariate analyses associated with the outcome of pain, older patients, those with higher baseline back pain, those with lesser reported disability and higher SF-12 MCS quality of life scores were associated with improved outcomes. For the multivariate analyses associated with the outcome of disability, presence of leg pain greater than back pain and no previous surgery suggested a better outcome.

conclusionsFor this study, several predictive variables were either unique or conflicted with those advocated in general prognostic literature, suggesting they may have value for clinical decision making for lumbar discectomy surgery. In particular, leg pain greater than back pain and older age may yield promising value. Other significant findings such as quality of life scores and prior surgery may yield less value since these findings are similar to those that are considered to be prognostic regardless of intervention type.

Indexed as

AdultAgedDisability EvaluationDiskectomyFemaleHumansLow Back PainLumbar VertebraeMaleMiddle AgedPain MeasurementPrognosisProspective StudiesQuality of LifeRetrospective StudiesTreatment OutcomeDiscectomyLow back painPrognosisSurgery

Identifiers

PMID25823517
OpenAlexW2089093283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.