Evidence map›Paper›PMID 25822730›Full record

SynthesisPloS one2015

Effectiveness of surgery for lumbar spinal stenosis: a systematic review and meta-analysis.

Gustavo C Machado, Paulo H Ferreira, Ian A Harris, Marina B Pinheiro, Bart W Koes, Maurits van Tulder, Magdalena Rzewuska, Chris G Maher, Manuela L Ferreira

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07291388 (Effectiveness of Retrolaminar Block in Reducing Postoperative Opioid Consumption in Patients Undergoing Lumbar Spine Fusion With Multimodal Analgesia), which is not on this map. Cited by 49 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 5 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07291388 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of Retrolaminar Block in Reducing Postoperative Opioid Consumption in Patients Undergoing Lumbar Spine Fusion With Multimodal Analgesia

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2026 to 2027Enrolled44ConditionsAcute Pain, Anesthesia, Lumbar Spine DiseaseArmsretrolaminar block, Sham block
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 5 syntheses or guidelines pooled it, 156 citations in OpenAlex.

  1. Pooled it
  2. A systematic review of developmental lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020
    Pooled it
  3. Reoperation of decompression alone or decompression plus fusion surgeries for degenerative lumbar diseases: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Pooled it
  4. The clinical course of pain and disability following surgery for spinal stenosis: a systematic review and meta-analysis of cohort studies.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Pooled it
  5. Surgical options for lumbar spinal stenosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Patients' experience on waiting for spinal arthrodesis: a qualitative study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Observational
  12. Article
  13. Article
  14. Association between acute pain trajectory and patient-reported outcomes at 6-months following lumbar surgery for patients with lumbar degenerative disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Interspinous and spinolaminar synthetic vertebropexy of the lumbar spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Gustavo C MachadoThe George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Paulo H FerreiraFaculty of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Ian A HarrisSouth Western Sydney Clinical School, Ingham Institute for Applied Medical Research, University of New South Wales, Sydney, NSW, Australia.
Marina B PinheiroFaculty of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Bart W KoesDepartment of General Practice, Erasmus Medical Centre, Rotterdam, The Netherlands.
Maurits van TulderDepartment of Health Sciences, VU University, Amsterdam, The Netherlands.
Magdalena RzewuskaThe George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Chris G MaherThe George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Manuela L FerreiraThe George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Institute of Bone and Joint Research, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
The George Institute for Global Health · AUUniversity of Sydney · AUErasmus University Rotterdam · NLIngham Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of spinal stenosis by surgery has increased rapidly in the past two decades, however, there is still controversy regarding the efficacy of surgery for this condition. Our aim was to investigate the efficacy and comparative effectiveness of surgery in the management of patients with lumbar spinal stenosis.

methodsElectronic searches were performed on MEDLINE, EMBASE, AMED, CINAHL, Web of Science, LILACS and Cochrane Library from inception to November 2014. Hand searches were conducted on included articles and relevant reviews. We included randomised controlled trials evaluating surgery compared to no treatment, placebo/sham, or to another surgical technique in patients with lumbar spinal stenosis. Primary outcome measures were pain, disability, recovery and quality of life. The PEDro scale was used for risk of bias assessment. Data were pooled with a random-effects model, and the GRADE approach was used to summarise conclusions.

resultsNineteen published reports (17 trials) were included. No trials were identified comparing surgery to no treatment or placebo/sham. Pooling revealed that decompression plus fusion is not superior to decompression alone for pain (mean difference -3.7, 95% confidence interval -15.6 to 8.1), disability (mean difference 9.8, 95% confidence interval -9.4 to 28.9), or walking ability (risk ratio 0.9, 95% confidence interval 0.4 to 1.9). Interspinous process spacer devices are slightly more effective than decompression plus fusion for disability (mean difference 5.7, 95% confidence interval 1.3 to 10.0), but they resulted in significantly higher reoperation rates when compared to decompression alone (28% v 7%, P < 0.001). There are no differences in the effectiveness between other surgical techniques for our main outcomes.

conclusionsThe relative efficacy of various surgical options for treatment of spinal stenosis remains uncertain. Decompression plus fusion is not more effective than decompression alone. Interspinous process spacer devices result in higher reoperation rates than bony decompression.

Indexed as

HumansLumbar VertebraeReoperationSpinal StenosisTreatment Outcome

Identifiers

PMID25822730
PMCPMC4378944
OpenAlexW2084383397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.