Evidence map›Paper›PMID 25822116›Full record

ArticleJournal of behavioral medicine2015

Impact of melanoma genetic test reporting on perceived control over melanoma prevention.

Lisa G Aspinwall, Tammy K Stump, Jennifer M Taber, Wendy Kohlmann, Samantha L Leaf, Sancy A Leachman

Abstract read
In one paragraph

Article in Journal of behavioral medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Testing Explanations for Skepticism of Personalized Risk Information.Medical decision making : an international journal of the Society for Medical Decision Making · 2023
    Article
  2. Interactive Beliefs about Genes and Behavior Predict Improved Sun Protection Following Melanoma Genetic Counseling.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lisa G AspinwallDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA. lisa.aspinwall@utah.edu.
Tammy K StumpDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA.
Jennifer M TaberDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA.
Wendy KohlmannHuntsman Cancer Institute, Salt Lake City, UT, USA.
Samantha L LeafDepartment of Psychology, University of Utah, 380 South 1530 East, Room 502, Salt Lake City, UT, 84112-0251, USA.
Sancy A LeachmanHuntsman Cancer Institute, Salt Lake City, UT, USA.
University of Utah · USHuntsman Cancer Institute · USOregon Health & Science University · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
Impact of Melanoma Genetic Testing on Health Cognitions and Prevention BehaviorsR01CA158322 · NCI · UNIVERSITY OF UTAH · PI ASPINWALL, LISA G, LEACHMAN, SANCY ANN · 2011 to 2016
$2.5M
University of Utah Center for Clinical and Translational Science-KL2KL2RR025763 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$972k
NCATS NIH HHS UL1 TR001067NCI NIH HHS 5P30CA420-14NCI NIH HHS N01 PC035141NCI NIH HHS N01-PC-35141NCI NIH HHS P30 CA042014NCI NIH HHS R01 CA158322NCI NIH HHS R01 CA158322-01NCRR NIH HHS 1KL2RR025763-01NCRR NIH HHS KL2 RR025763
6 · The paper itself

Abstract

To determine whether receiving melanoma genetic test results undermines perceived control over melanoma prevention, control-related beliefs were examined among 60 adults from melanoma-prone families receiving CDKN2A/p16 test results (27 unaffected noncarriers, 15 unaffected carriers, 18 affected carriers; response rate at 2 years = 64.9 % of eligible respondents). Multilevel modeling of perceived control ratings over a 2-year period revealed significant variation in individual trajectories: most participants showed increases (45 %) or no change (38.3 %), while 16.7 % showed decreases. At the group level, noncarriers reported sustained increases through the 2-year follow-up (ps < .05); unaffected carriers reported significant short-term increases (ps < .05); and affected carriers reported no change. Participants in all groups continued to rate photoprotection as highly effective in reducing melanoma risk and reported decreased beliefs that carrying the p16 mutation would inevitably lead to the development of melanoma. Qualitative responses immediately following counseling and test reporting corroborated these findings, as 93 % indicated it was possible to either prevent (64.9 %) or decrease the likelihood (28.1 %) of future melanomas. Thus, genetic test reporting does not generally undermine perceived control over melanoma prevention, though variability in response to positive results warrants future study.

Indexed as

Genetic CounselingGenetic Predisposition to DiseaseGenetic TestingInternal-External ControlAdultCutaneous Malignant MelanomaCyclin-Dependent Kinase Inhibitor p16FemaleHumansMaleMelanomaMiddle AgedSkin NeoplasmsCyclin-Dependent Kinase Inhibitor p16CDKN2A/p16Familial melanomaGenetic counselingGenetic determinismPerceived controlPrevention

Identifiers

PMID25822116
PMCPMC4568125
OpenAlexW2082889118

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.