Evidence map›Paper›PMID 25821837›Full record

ArticleAnnual review of virology

Viruses and the Microbiota.

Christopher M Robinson, Julie K Pfeiffer

Abstract read
In one paragraph

Article in Annual review of virology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Oral and plasma microbiome in the context of acute febrile illness.medRxiv : the preprint server for health sciences · 2026
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher M RobinsonDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
Julie K PfeifferDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390.

Funding

MOLECULAR MICROBIOLOGY TRAINING GRANTT32AI007520 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 1997 to 2026
$7.0M
The influence of host barriers on viral quasispecies diversity and pathogenesisR01AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PFEIFFER, JULIE K · 2008 to 2022
$6.0M
Enteric virus-microbiota interactionsR37AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 2023 to 2026
$2.5M
Infectious Diseases Training ProgramT32AI070116 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PERL, TRISH M. · 2007 to 2017
$1.1M
NIAID NIH HHS R01 AI074668NIAID NIH HHS R37 AI074668NIAID NIH HHS T32 AI007520NIAID NIH HHS T32 AI070116
6 · The paper itself

Abstract

Every surface of the human body is colonized by a diverse microbial community called the microbiota, yet the impact of microbiota on viruses is unclear. Recent research has advanced our understanding of how microbiota influence viral infection. Microbiota inhibit infection of some viruses and promote infection of other viruses. These effects can occur through direct and/or indirect effects on the host and/or virus. This review examines the known effects and mechanisms by which the microbiota influence mammalian virus infections. Furthermore, we suggest strategies for future research on how microbiota impact viruses. Overall, microbiota may influence a wide array of viruses through diverse mechanisms, making the study of virus-microbiota interactions a fertile area for future investigation.

Indexed as

bacteriainnate immunitymicrobiotavirus

Identifiers

PMID25821837
PMCPMC4373533

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.