Evidence map›Paper›PMID 25821718›Full record

ArticleCurrent molecular imaging2014

Molecular Imaging in Optical Coherence Tomography.

Scott P Mattison, Wihan Kim, Jesung Park, Brian E Applegate

Abstract read
In one paragraph

Article in Current molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. In vivo optical molecular imaging of inflammation and immunity.Journal of molecular medicine (Berlin, Germany) · 2021
    Review
  5. Review
  6. Review
  7. Embryonic Mouse Cardiodynamic OCT Imaging.Journal of cardiovascular development and disease · 2020
    Review
  8. Repurposing Molecular Imaging and Sensing for Cancer Image-Guided Surgery.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Review
  9. Article
  10. Molecular Imaging of the Heart.Comprehensive Physiology · 2019
    Review
  11. Article
  12. Article
  13. Retinal and choroidal imagingProceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Scott P MattisonDepartment of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, TX 77843.
Wihan KimDepartment of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, TX 77843.
Jesung ParkDepartment of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, TX 77843.
Brian E ApplegateDepartment of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, TX 77843.

Funding

Morphological and Molecular Imaging System for in vivo Atherosclerosis ResearchR01HL111361 · NHLBI · TEXAS ENGINEERING EXPERIMENT STATION · PI APPLEGATE, BRIAN E. · 2012 to 2016
$1.7M
Combined OCT/FLIM Biochemical and Anatomical Imaging for Early Cancer DiagnosisR21CA132433 · NCI · TEXAS ENGINEERING EXPERIMENT STATION · PI JO, JAVIER ANTONIO · 2008 to 2009
$668k
Development of high-resolution molecular imaging of endogenous chromophores withR21RR025799 · NCRR · TEXAS ENGINEERING EXPERIMENT STATION · PI APPLEGATE, BRIAN E. · 2009 to 2011
$504k
New Technologies for high resolution optical molecular imagingR21EB007729 · NIBIB · TEXAS ENGINEERING EXPERIMENT STATION · PI APPLEGATE, BRIAN E. · 2008 to 2009
$383k
NCI NIH HHS R21 CA132433NCRR NIH HHS R21 RR025799NHLBI NIH HHS R01 HL111361NIBIB NIH HHS R21 EB007729
6 · The paper itself

Abstract

Optical coherence tomography (OCT) is a medical imaging technique that provides tomographic images at micron scales in three dimensions and high speeds. The addition of molecular contrast to the available morphological image holds great promise for extending OCT's impact in clinical practice and beyond. Fundamental limitations prevent OCT from directly taking advantage of powerful molecular processes such as fluorescence emission and incoherent Raman scattering. A wide range of approaches is being researched to provide molecular contrast to OCT. Here we review those approaches with particular attention to those that derive their molecular contrast directly from modulation of the OCT signal. We also provide a brief overview of the multimodal approaches to gaining molecular contrast coincident with OCT.

Identifiers

PMID25821718
PMCPMC4373611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.