Evidence map›Paper›PMID 25821510›Full record

ArticleComputational and mathematical methods in medicine2015

Transmission dynamics of resistant bacteria in a predator-prey system.

Xubin Gao, Qiuhui Pan, Mingfeng He

Abstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xubin GaoSchool of Mathematical Sciences, Dalian University of Technology, Dalian 116024, China ; City institute, Dalian University of Technology, Dalian 116600, China.
Qiuhui PanSchool of Mathematical Sciences, Dalian University of Technology, Dalian 116024, China ; School of Innovation Experiment, Dalian University of Technology, Dalian 116024, China.
Mingfeng HeSchool of Mathematical Sciences, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0003-4484-5315

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper discusses the impact on human health caused by the addition of antibiotics in the feed of food animals. We use the established transmission rule of resistant bacteria and combine it with a predator-prey system to determine a differential equations model. The equations have three steady equilibrium points corresponding to three population dynamics states under the influence of resistant bacteria. In order to quantitatively analyze the stability of the equilibrium points, we focused on the basic reproduction numbers. Then, both the local and global stability of the equilibrium points were quantitatively analyzed by using essential mathematical methods. Numerical results are provided to relate our model properties to some interesting biological cases. Finally, we discuss the effect of the two main parameters of the model, the proportion of antibiotics added to feed and the predation rate, and estimate the human health impacts related to the amount of feed antibiotics used. We further propose an approach for the prevention of the large-scale spread of resistant bacteria and illustrate the necessity of controlling the amount of in-feed antibiotics used.

Indexed as

Animal FeedFood MicrobiologyPredatory BehaviorAlgorithmsAnimalsAnti-Bacterial AgentsBacterial InfectionsComputer SimulationDrug Resistance, BacterialFood ChainFood SafetyHumansMeatModels, TheoreticalPopulation DynamicsAnti-Bacterial Agents

Identifiers

PMID25821510
PMCPMC4364376

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.