Evidence map›Paper›PMID 25821459›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2015

DNA damage in BALB/c mice infected with Lacazia loboi and its relation to nutritional status.

Adriana Sierra Assencio Almeida Barbosa, Larissa Ragozo Cardoso de Oliveira, Francilene Capel Tavares, Carlos Roberto Gonçalves de Lima, Suzana Madeira Diório, Sueli Aparecida Calvi, Fátima Regina Vilani-Moreno, Paulo Câmara Marques Pereira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adriana Sierra Assencio Almeida BarbosaBiology Technical Team, Lauro de Souza Lima Institute, Bauru, São Paulo State Brazil ; Equipe Técnica de Biologia, Instituto Lauro de Souza Lima, Rod. Comte. João Ribeiro de Barros, km 225/226, CEP 17.034-971 Bauru, SP Brazil.
Larissa Ragozo Cardoso de OliveiraDepartment of Tropical Diseases and Image Diagnosis, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State Brazil.
Francilene Capel TavaresDepartment of Tropical Diseases and Image Diagnosis, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State Brazil.
Carlos Roberto Gonçalves de LimaDepartment of Tropical Diseases and Image Diagnosis, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State Brazil.
Suzana Madeira DiórioMicrobiology Technical Team, Lauro de Souza Lima Institute, Bauru, São Paulo State Brazil.
Sueli Aparecida CalviDepartment of Tropical Diseases and Image Diagnosis, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State Brazil.
Fátima Regina Vilani-MorenoBiology Technical Team, Lauro de Souza Lima Institute, Bauru, São Paulo State Brazil.
Paulo Câmara Marques PereiraDepartment of Tropical Diseases and Image Diagnosis, Botucatu Medical School, São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo State Brazil.
Universidade Estadual Paulista (Unesp) · BRInstituto Lauro de Souza Lima · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundJorge Lobo's disease, also known as lacaziosis, is a cutaneous-subcutaneous mycosis with chronic evolution. It is caused by the fungus Lacazia loboi. Herein we report a study that relates the genotoxicity caused by L. loboi in isogenic mice with nutritional status, through a normal or restricted diet.

methodsDNA damage was assessed in the peripheral blood by the comet assay (tail intensity).

resultsThe results for leukocytes showed increases in the mean tail intensity in mice under dietary restriction, in infected mice under dietary restriction and in infected mice ingesting a normal diet.

conclusionThese results indicate that dietary restriction and L. loboi infection may increase DNA damage levels in mice, as detected by the comet assay.

Indexed as

Comet assayGenotoxicityJorge Lobo’ diseaseLacazia loboiMalnutritionMice

Identifiers

PMID25821459
PMCPMC4376161
OpenAlexW2162315390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.