Evidence map›Paper›PMID 25821449›Full record

ReviewFrontiers in immunology2015

Microbiota and mucosal immunity in amphibians.

Bruno M Colombo, Thibault Scalvenzi, Sarah Benlamara, Nicolas Pollet

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Organ-Specific Shifts in Aerobic and Anaerobic Metabolism Throughout Metamorphosis Into Adulthood in a Fully Aquatic Amphibian.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  10. Article
  11. The Gut Microbiome of the Asiatic Toad (Ecology and evolution · 2025
    Article
  12. Research Status and Prospect of Amphibian Symbiotic Microbiota.Animals : an open access journal from MDPI · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bruno M ColomboInstitute of Systems and Synthetic Biology, Université d'Evry Val d'Essonne , Evry , France.
Thibault ScalvenziInstitute of Systems and Synthetic Biology, Université d'Evry Val d'Essonne , Evry , France.
Sarah BenlamaraInstitute of Systems and Synthetic Biology, Université d'Evry Val d'Essonne , Evry , France.
Nicolas PolletInstitute of Systems and Synthetic Biology, CNRS , Evry , France ; Evolution, Genome, Comportement et Ecologie, CNRS, Université Paris-Sud, IRD , Gif-sur-Yvette , France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We know that animals live in a world dominated by bacteria. In the last 20 years, we have learned that microbes are essential regulators of mucosal immunity. Bacteria, archeas, and viruses influence different aspects of mucosal development and function. Yet, the literature mainly covers findings obtained in mammals. In this review, we focus on two major themes that emerge from the comparative analysis of mammals and amphibians. These themes concern: (i) the structure and functions of lymphoid organs and immune cells in amphibians, with a focus on the gut mucosal immune system; and (ii) the characteristics of the amphibian microbiota and its influence on mucosal immunity. Lastly, we propose to use Xenopus tadpoles as an alternative small-animal model to improve the fundamental knowledge on immunological functions of gut microbiota.

Indexed as

chytridmicrobiomemucosal immunitysmall-animal modelXenopus

Identifiers

PMID25821449
PMCPMC4358222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.