Evidence map›Paper›PMID 25821058›Full record

ArticleWiener klinische Wochenschrift2015

HUIEC, Human intestinal epithelial cell line with differentiated properties: process of isolation and characterisation.

Lidija Gradisnik, Martin Trapecar, Marjan Slak Rupnik, Tomaz Velnar

Abstract read
PubMed Publisher
In one paragraph

Article in Wiener klinische Wochenschrift, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Gastrointestinal tract, its pathophysiology andWorld journal of gastroenterology · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Gynaecological cancers and their cell lines.Journal of cellular and molecular medicine · 2021
    Review
  6. DifferentPlants (Basel, Switzerland) · 2021
    Article
  7. Article
  8. CYP2C9, a Metabolic CYP450s Enzyme, Plays Critical Roles in Activating Ellagic Acid in Human Intestinal Epithelial Cells.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  9. Endometrial cancer and its cell lines.Molecular biology reports · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lidija GradisnikLaboratory for Cell Cultures, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Martin TrapecarLaboratory for Cell Cultures, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Marjan Slak RupnikInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Tomaz VelnarDepartment of Neurosurgery, University Medical Centre Maribor, Ljubljanska ulica 5, 2000, Maribor, Slovenia. tvelnar@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal epithelium is composed of diverse cell types, most abundant being the enterocytes. Among other functions, they maintain the intestinal barrier and play a critical role in the absorption of nutrients, drugs and toxins. This study describes the development and characterization of human intestinal epithelial cells (HUIEC), a spontaneously arising cell line established by selective trypsinization and cloning of the intestinal epithelium, resulting in a uniform population of highly epithelial cells with a strong growth potential.

Indexed as

Batch Cell Culture TechniquesCell DifferentiationCell LineCell SeparationEpithelial CellsHumansIntestinal MucosaCell isolationCell lineCell modelIntestinal epithelial cellsIntestinal epithelium

Identifiers

PMID25821058

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.