SynthesisScientific reports2015
Association of body mass index with chromosome damage levels and lung cancer risk among males.
Synthesis in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Body mass index (BMI) and risk of lung cancer: a systematic review and meta-analysis of studies using directly measured and genetically proxied measures of BMI.Cancer causes & control : CCC · 2026Pooled it
- The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Association between metabolically healthy obesity and metastasis in lung cancer patients - a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Pooled it
- The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study.Scientific reports · 2016Trial
- Analysis of the morbidity characteristics and related factors of pulmonary nodules in patients with type 2 diabetes mellitus: a retrospective study.BMC endocrine disorders · 2025Article
- Influence of Body Mass Index and Duration of Disease on Chromosome Damage in Lymphocytes of Patients with Diabetes.Life (Basel, Switzerland) · 2023Article
- Statistical Assessment of Toxic and Essential Metals in the Serum of Female Patients with Lung Carcinoma from Pakistan.Biological trace element research · 2020Article
- Environmental Monitoring of PAHs Exposure, Biomarkers and Vital Status in Coke Oven Workers.International journal of environmental research and public health · 2020Article
- The Obesity Paradox in Lung Cancer: Associations With Body Size Versus Body Shape.Frontiers in oncology · 2020Article
- A paradox or a challenge?Journal of thoracic disease · 2019Article
- Overall and Central Obesity and Risk of Lung Cancer: A Pooled Analysis.Journal of the National Cancer Institute · 2018Article
- Body mass index and lung cancer risk: a pooled analysis based on nested case-control studies from four cohort studies.BMC cancer · 2018Article
- The clinicopathological and prognostic features of Chinese and Japanese inpatients with lung cancer.Oncotarget · 2016Article
- Anthropometry and the Risk of Lung Cancer in EPIC.American journal of epidemiology · 2016Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological studies have shown an etiological link between body mass index (BMI) and cancer risk, but evidence supporting these observations is limited. This study aimed to investigate potential associations of BMI with chromosome damage levels and lung cancer risk. First, we recruited 1333 male workers from a coke-oven plant to examine their chromosome damage levels; and then, a cohort study of 12,052 males was used to investigate the association of BMI with lung cancer incidence. We further carried out a meta-analysis for BMI and male lung cancer risk based on cohort studies. We found that men workers with excess body weight (BMI ≥ 25 kg/m(2)) had lower levels of MN frequencies than men with normal-weight (BMI: 18.5-24.9). Our cohort study indicated that, the relative risk (RR) for men with BMI ≥ 25 to develop lung cancer was 35% lower than RR for normal-weight men. Further meta-analysis showed that, compared to normal-weight men, men with BMI ≥ 25 had decreased risk of lung cancer among both the East-Asians and others populations. These results indicate that men with excess body weight had significant decreased chromosome damage levels and lower risk of lung cancer than those with normal-weight. However, further biological researches were needed to validate these associations.
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