ArticleApplied and environmental microbiology2015
Amphibian Symbiotic Bacteria Do Not Show a Universal Ability To Inhibit Growth of the Global Panzootic Lineage of Batrachochytrium dendrobatidis.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Host and Environmental Factors Outweigh Pathogen in Shaping Skin Microbiome of a Threatened Andean Amphibian Community.Molecular ecology · 2026Article
- Priority effects alter microbiome composition and increase abundance of probiotic taxa in treefrog tadpoles.Applied and environmental microbiology · 2024Article
- Low-level pathogen infection and geographic location correlate with the skin microbiomes of Columbia spotted frogs (Current research in microbial sciences · 2024Article
- Effects of temperature on the interaction between amphibian skin bacteria andFrontiers in microbiology · 2023Article
- Comparative Analysis of Skin Bacterial Diversity and Its Potential Antifungal Function Between Desert and Pine Forest Populations of Boreal Toads Anaxyrus boreas.Microbial ecology · 2022Article
- Microbial Diversity of the Chinese Tiger Frog (Animals : an open access journal from MDPI · 2022Article
- Functional Redundancy of Batrachochytrium dendrobatidis Inhibition in Bacterial Communities Isolated from Lithobates clamitans Skin.Microbial ecology · 2020Article
- Microbiota and skin defense peptides may facilitate coexistence of two sympatric Andean frog species with a lethal pathogen.The ISME journal · 2019Article
- Skin-associated lactic acid bacteria from North American bullfrogs as potential control agents of Batrachochytrium dendrobatidis.PloS one · 2019Article
- Captivity and Infection by the Fungal PathogenFrontiers in microbiology · 2019Article
- Designing Probiotic Therapies With Broad-Spectrum Activity Against a Wildlife Pathogen.Frontiers in microbiology · 2019Article
- Amphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure.Nature communications · 2018Article
- Widespread Elevational Occurrence of Antifungal Bacteria in Andean Amphibians Decimated by Disease: A Complex Role for Skin Symbionts in Defense Against Chytridiomycosis.Frontiers in microbiology · 2018Article
- Assessment of Bacterial Communities Associated With the Skin of Costa Rican Amphibians at La Selva Biological Station.Frontiers in microbiology · 2018Article
- Comparing the bacterial communities of wild and captive golden mantella frogs: Implications for amphibian conservation.PloS one · 2018Article
- Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians.Journal of the Royal Society, Interface · 2017Article
- Amphibian skin microbiota exhibits temporal variation in community structure but stability of predicted Bd-inhibitory function.The ISME journal · 2017Article
- Greater Species Richness of Bacterial Skin Symbionts Better Suppresses the Amphibian Fungal Pathogen Batrachochytrium Dendrobatidis.Microbial ecology · 2017Article
- Antifungal Bacteria on Woodland Salamander Skin Exhibit High Taxonomic Diversity and Geographic Variability.Applied and environmental microbiology · 2017Article
- Planarian regeneration in space: Persistent anatomical, behavioral, and bacteriological changes induced by space travel.Regeneration (Oxford, England) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Microbiomes associated with multicellular organisms influence the disease susceptibility of hosts. The potential exists for such bacteria to protect wildlife from infectious diseases, particularly in the case of the globally distributed and highly virulent fungal pathogen Batrachochytrium dendrobatidis of the global panzootic lineage (B. dendrobatidis GPL), responsible for mass extinctions and population declines of amphibians. B. dendrobatidis GPL exhibits wide genotypic and virulence variation, and the ability of candidate probiotics to restrict growth across B. dendrobatidis isolates has not previously been considered. Here we show that only a small proportion of candidate probiotics exhibited broad-spectrum inhibition across B. dendrobatidis GPL isolates. Moreover, some bacterial genera showed significantly greater inhibition than others, but overall, genus and species were not particularly reliable predictors of inhibitory capabilities. These findings indicate that bacterial consortia are likely to offer a more stable and effective approach to probiotics, particularly if related bacteria are selected from genera with greater antimicrobial capabilities. Together these results highlight a complex interaction between pathogens and host-associated symbiotic bacteria that will require consideration in the development of bacterial probiotics for wildlife conservation. Future efforts to construct protective microbiomes should incorporate bacteria that exhibit broad-spectrum inhibition of B. dendrobatidis GPL isolates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.