Evidence map›Paper›PMID 25819815›Full record

ArticleBMJ case reports2015

Prostate cancer: beware of disseminated intravascular coagulation.

Mihir Desai, Babbin John, Gillian Evans, Ben Eddy

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mihir DesaiDepartment of Medicine, Canterbury Hospital, Canterury, Kent, UK.
Babbin JohnDepartment of Urology, Canterbury Hospital, Canterbury, Kent, UK.
Gillian EvansDepartment of Haematology, Canterbury Hospital, Canterbury, Kent, UK.
Ben EddyDepartment of Urology, Canterbury Hospital, Canterbury, Kent, UK.
Kent and Canterbury Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated intravascular coagulation (DIC) is a pathological systemic condition resulting from aberrant activation of the coagulation system. It is characterised by the release and activation of procoagulants into the blood, with an associated consumption coagulopathy. Its association with solid and haematological malignancies is well described in literature. This case describes an elderly man, known to have prostate cancer, who following transurethral resection of the prostate developed DIC with haematuria, spontaneous ecchymoses and mucosal bleeding. Subsequent investigations revealed a prostate-specific antigen (PSA) >1000 µg/L, and staging CT showed multiple sclerotic metastatic lesions affecting the thoracic and lumbar vertebra, as well as infiltration into his left femur. Coagulation normalised with blood products and vitamin K within 1 week, and the patient responded to antiandrogen therapy with a reduction in pain and PSA on discharge.

Indexed as

Aged, 80 and overAndrogen AntagonistsAntifibrinolytic AgentsBiomarkers, TumorDiagnosis, DifferentialDisseminated Intravascular CoagulationHematuriaHumansMaleProstate-Specific AntigenProstatic NeoplasmsSpinal NeoplasmsTreatment OutcomeVitamin KAndrogen AntagonistsAntifibrinolytic AgentsBiomarkers, TumorProstate-Specific AntigenVitamin K

Identifiers

PMID25819815
PMCPMC4386315
OpenAlexW2091893343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.