ArticlePlant physiology2015
Salt stress reduces root meristem size by nitric oxide-mediated modulation of auxin accumulation and signaling in Arabidopsis.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 146 papers, 1 of them a synthesis that pooled it.
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Who cites it
146 citing papers in PubMed, 1 synthesis or guideline pooled it, 381 citations in OpenAlex.
- Loss-of-Function Mutation of ACTIN-RELATED PROTEIN 6 (ARP6) Impairs Root Growth in Response to Salinity Stress.Molecular biotechnology · 2023Pooled it
- Auxin is involved in NtIAA17-mediated regulation of root development under salt stress in tobacco.Planta · 2026Article
- Acetylcholine as a shield: enhancing growth and salt tolerance in pepper through ionic homeostasis, hormonal regulation, antioxidant defence and gene expression.Protoplasma · 2026Article
- Rhizobacteria-Mediated Reprogramming of Phytohormone Landscapes for Mitigating Salinity Stress in Plants.International journal of molecular sciences · 2026Review
- Abscisic acid interplay with phytohormones, plant growth regulators and signaling molecules in orchestrating an elaborate crosstalk for stress resilience in plants.Biologia futura · 2026Review
- Article
- The architecture of salt tolerance: A multi-scale view of sodium transport in plants.Plant communications · 2026Review
- Targeted metabolomic and gene expression analysis reveals an organ-specific response to chronic ionizing radiation exposure during Pinus sylvestris seedling development.BMC plant biology · 2026Article
- SQUAMOSA-Promoter Binding Protein Like 10/14 (OsSPL10/14) Regulate Salt Tolerance by Modulating Reactive Oxygen Species Homeostasis in Rice (Oryza Sativa L.).Rice (New York, N.Y.) · 2025Article
- A Novel Breeding Target for Salt-Tolerant Maize:Plants (Basel, Switzerland) · 2025Article
- The Hidden Architects: Nitric Oxide and Redox Dynamics in Plant Stem Cell Homeostasis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Sophisticated crosstalk of tryptophan-derived metabolites in plant stress responses.Plant communications · 2025Review
- Response of hidden architects to salt stress.Planta · 2025Review
- Unravelling root system architecture plasticity in response to abiotic stresses in maize.Scientific reports · 2025Article
- Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (Plants (Basel, Switzerland) · 2025Article
- The stress-induced gene AtDUF569 positively regulates salt stress responses in Arabidopsis thaliana.BMC plant biology · 2025Article
- Salt stress-accelerated proteasomal degradation of LBD11 suppresses ROS-mediated meristem development and root growth in Arabidopsis.Plant communications · 2025Article
- Cerium oxide nanoparticles alleviate drought stress in apple seedlings by regulating ion homeostasis, antioxidant defense, gene expression, and phytohormone balance.Scientific reports · 2025Article
- A large-scale gene co-expression network analysis reveals Glutamate Dehydrogenase 2 (GhGDH2_D03) as a hub regulator of salt and salt-alkali tolerance in cotton.Plant molecular biology · 2025Article
- Salinity survival: molecular mechanisms and adaptive strategies in plants.Frontiers in plant science · 2025Review
86 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of the plant root system is highly plastic, which allows the plant to adapt to various environmental stresses. Salt stress inhibits root elongation by reducing the size of the root meristem. However, the mechanism underlying this process remains unclear. In this study, we explored whether and how auxin and nitric oxide (NO) are involved in salt-mediated inhibition of root meristem growth in Arabidopsis (Arabidopsis thaliana) using physiological, pharmacological, and genetic approaches. We found that salt stress significantly reduced root meristem size by down-regulating the expression of PINFORMED (PIN) genes, thereby reducing auxin levels. In addition, salt stress promoted AUXIN RESISTANT3 (AXR3)/INDOLE-3-ACETIC ACID17 (IAA17) stabilization, which repressed auxin signaling during this process. Furthermore, salt stress stimulated NO accumulation, whereas blocking NO production with the inhibitor N(ω)-nitro-l-arginine-methylester compromised the salt-mediated reduction of root meristem size, PIN down-regulation, and stabilization of AXR3/IAA17, indicating that NO is involved in salt-mediated inhibition of root meristem growth. Taken together, these findings suggest that salt stress inhibits root meristem growth by repressing PIN expression (thereby reducing auxin levels) and stabilizing IAA17 (thereby repressing auxin signaling) via increasing NO levels.
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