Evidence map›Paper›PMID 25818663›Full record

ReviewCold Spring Harbor perspectives in medicine2015

Human Endometrial Transcriptomics: Implications for Embryonic Implantation.

Eva Gómez, Maria Ruíz-Alonso, Jose Miravet, Carlos Simón

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Pathophysiology and Management of Placenta Accreta Spectrum.Journal of developmental biology · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Automation in ART: Paving the Way for the Future of Infertility Treatment.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. One Plus One is Better than Two: An Approach Towards a Single Blastocyst Transfer Policy for All IVF Patients.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Understanding the Impact of Uterine Fibroids on Human Endometrium Function.Frontiers in cell and developmental biology · 2021
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva GómezIGENOMIX, Parc Cientific Valencia University, Paterna, 46980 Valencia, Spain.
Maria Ruíz-AlonsoIGENOMIX, Parc Cientific Valencia University, Paterna, 46980 Valencia, Spain.
Jose MiravetIGENOMIX, Parc Cientific Valencia University, Paterna, 46980 Valencia, Spain.
Carlos SimónIGENOMIX, Parc Cientific Valencia University, Paterna, 46980 Valencia, Spain Fundación Instituto Valenciano de Infertilidad (FIVI), Department of Obstetrics and Gynecology, School of Medicine, Valencia University and Instituto Universitario IVI/INCLIVA, 46010 Valencia, Spain Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human endometrium has been extensively investigated in the search for markers capable of predicting its receptive status. The completion of the Human Genome Project has triggered a rapid development of new fields in molecular biology, the "transcriptomics" being a major turning point in the knowledge acquisition of endometrial receptivity. Based on this, a customized Endometrial Receptivity Array (ERA) has been developed, which is capable of identifying the genomic signature of receptivity. This diagnostic tool showed that the window of implantation (WOI) is displaced in one out of four patients with implantation failure, allowing the identification of their personalized WOI. This strategy allows performing a personalized embryo transfer (pET) on the day in which the endometrium is receptive. The combination of a systems biology approach and next-generation sequencing will overcome the limitations of microarrays, and will, in the future, allow elucidation of the mechanisms involved in embryo implantation.

Indexed as

BiomarkersEmbryo ImplantationEmbryo TransferEndometriumFemaleGene Expression ProfilingHumansBiomarkers

Identifiers

PMID25818663
PMCPMC4484960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.