Evidence map›Paper›PMID 25817583›Full record

ReviewNature reviews. Microbiology2015

Tackling antibiotic resistance: the environmental framework.

Thomas U Berendonk, Célia M Manaia, Christophe Merlin, Despo Fatta-Kassinos, Eddie Cytryn, Fiona Walsh, Helmut Bürgmann, Henning Sørum, Madelaine Norström, Marie-Noëlle Pons and 7 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 637 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
637citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

637 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Spore-formingApplied and environmental microbiology · 2026
    Article
  7. The Spread of Antibiotic Resistance in Natural Environments.Antibiotics (Basel, Switzerland) · 2026
    Article
  8. Pairwise Growth Dynamics of EnvironmentalAntibiotics (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

577 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Thomas U Berendonk1] Institute for Hydrobiology, Technische Universität Dresden, Dresden 01062, Germany. [2].
Célia M Manaia1] Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Arquiteto Lobão Vital, Apartado 2511, Porto 4202-401, Portugal. [2].
Christophe MerlinUniversité de Lorraine and le Centre National de la Recherche Scientifique, Laboratoire de Chimie Physique et Microbiologie pour l'Environnement, Unite Mixte de Recherche 7564, Vandoeuvre-lès-Nancy F-54500, France.
Despo Fatta-KassinosCivil and Environmental Engineering Department and Nireas, International Water Research Center, University of Cyprus, PO Box 20537, Nicosia 1678, Cyprus.
Eddie CytrynInstitute of Soil, Water and Environmental Sciences, Volcani Center, Agricultural Research Organization, PO Box 6, Bet Dagan 50250, Israel.
Fiona WalshDepartment of Biology, Biosciences and Electronic Engineering Building, National University of Ireland Maynooth, Maynooth, County Kildare, Ireland.
Helmut BürgmannEawag: Swiss Federal Institute of Aquatic Science and Technology, Department of Surface Waters - Research and Management, Kastanienbaum (LU) 6047, Switzerland.
Henning SørumNorwegian University of Life Sciences, Faculty of Veterinary Medicine and Life Sciences, Department of Food Safety and Infection Biology, PO Box 8146 Dep, Oslo N-0033, Norway.
Madelaine NorströmNorwegian Veterinary Institute, Department of Epidemiology, Oslo N-0106, Norway.
Marie-Noëlle PonsLaboratoire Reactions et Génie des Procédés (UMR CNRS 7274), Université de Lorraine, Nancy 54000, France.
Norbert KreuzingerVienna University of Technology, Institute of Water Quality, Resources and Waste Management, Karlsplatz 13/226, Vienna 1040, Austria.
Pentti HuovinenDepartment of Medical Microbiology and Immunology, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland.
Stefania StefaniLaboratory of Molecular Microbiology and Antibiotic Resistance, Department of Biomedical Sciences, University of Catania, Via Androne 81, Catania 95124, Italy.
Thomas SchwartzKarlsruhe Institute of Technology Campus North, Institute of Functional Interfaces, Microbiology of Natural and Technical Interfaces Department, Hermann-von-Helmholtz-Platz 1, Eggenstein-Leopoldshafen 76344, Germany.
Veljo KisandInstitute of Technology, Tartu University, Nooruse 1, Tartu 50411, Estonia.
Fernando BaqueroRamón y Cajal Institute for Health Research, Ramón y Cajal University Hospital, Department of Microbiology, Madrid 28034, Spain.
José Luis MartinezDepartamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones, Darwin 3, Cantoblanco, Madrid 28049, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance is a threat to human and animal health worldwide, and key measures are required to reduce the risks posed by antibiotic resistance genes that occur in the environment. These measures include the identification of critical points of control, the development of reliable surveillance and risk assessment procedures, and the implementation of technological solutions that can prevent environmental contamination with antibiotic resistant bacteria and genes. In this Opinion article, we discuss the main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment.

Indexed as

Health PolicyHuman ActivitiesAnimalsAnti-Bacterial AgentsDrug Resistance, BacterialEnvironmental MicrobiologyGene Expression Regulation, BacterialHumansAnti-Bacterial Agents

Identifiers

PMID25817583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.