ArticleEnvironmental health perspectives2015
Long-Term Ambient Residential Traffic-Related Exposures and Measurement Error-Adjusted Risk of Incident Lung Cancer in the Netherlands Cohort Study on Diet and Cancer.
Article in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026Pooled it
- Long-term exposure to elemental carbon and disease incidence: a systematic review and meta-analysis.Environmental health : a global access science source · 2025Pooled it
- Assessing the Global Impact of Ambient Air Pollution on Cancer Incidence and Mortality: A Comprehensive Meta-Analysis.JCO global oncology · 2024Pooled it
- Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis.Oncotarget · 2017Pooled it
- The association between PMEnvironmental research · 2026Article
- Exposure measurement error in air-pollution epidemiology and its determinants: results from the MELONS study.International journal of epidemiology · 2026Article
- Causal Concentration-Response Modeling with Continuous Curves and Exposure Error Correction:Environmental health perspectives · 2025Article
- Particulate matter air pollution as a cause of lung cancer: epidemiological and experimental evidence.British journal of cancer · 2025Review
- Investigating the Consequences of Measurement Error of Gradually More Sophisticated Long-Term Personal Exposure Models in Assessing Health Effects: The London Study (MELONS).Research report (Health Effects Institute) · 2025Article
- Air pollution and respiratory health in patients with COPD: should we focus on indoor or outdoor sources?Thorax · 2024Article
- Understanding the Cardiovascular and Metabolic Health Effects of Air Pollution in the Context of Cumulative Exposomic Impacts.Circulation research · 2024Review
- Long-term exposure to ambient PM2.5, particulate constituents and hospital admissions from non-respiratory infection.Nature communications · 2024Article
- Interpretable Machine Learning Approaches for Forecasting and Predicting Air Pollution: A Systematic Review.Aerosol and air quality research · 2024Article
- Exposure to low-level ambient air pollution and the relationship with lung and bladder cancer in older men, in Perth, Western Australia.British journal of cancer · 2023Article
- Review
- Measurement error correction for ambient PMEnvironmental research · 2023Article
- Exposure to diesel engine exhaust and alterations to the Cys34/Lys525 adductome of human serum albumin.Environmental toxicology and pharmacology · 2022Article
- Long-term nitrogen dioxide exposure and cause-specific mortality in the U.S. Medicare population.Environmental research · 2022Article
- Personal exposure levels to OEnvironmental monitoring and assessment · 2021Article
- Cohort studies of long-term exposure to outdoor particulate matter and risks of cancer: A systematic review and meta-analysis.Innovation (Cambridge (Mass.)) · 2021Review
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7 authors.
Funding
Abstract
backgroundThe International Agency for Research on Cancer (IARC) recently declared air pollution carcinogenic to humans. However, no study of air pollution and lung cancer to date has incorporated adjustment for exposure measurement error, and few have examined specific histological subtypes.
objectivesOur aim was to assess the association of air pollution and incident lung cancer in the Netherlands Cohort Study on Diet and Cancer and the impact of measurement error on these associations.
methodsThe cohort was followed from 1986 through 2003, and 3,355 incident cases were identified. Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals, for long-term exposures to nitrogen dioxide (NO2), black smoke (BS), PM2.5 (particulate matter with diameter ≤ 2.5 μm), and measures of roadway proximity and traffic volume, adjusted for potential confounders. Information from a previous validation study was used to correct the effect estimates for measurement error.
resultsWe observed elevated risks of incident lung cancer with exposure to BS [hazard ratio (HR) = 1.16; 95% CI: 1.02, 1.32, per 10 μg/m3], NO2 (HR = 1.29; 95% CI: 1.08, 1.54, per 30 μg/m3), PM2.5 (HR = 1.17; 95% CI: 0.93, 1.47, per 10 μg/m3), and with measures of traffic at the baseline address. The exposures were positively associated with all lung cancer subtypes. After adjustment for measurement error, the HRs increased and the 95% CIs widened [HR = 1.19 (95% CI: 1.02, 1.39) for BS and HR = 1.37 (95% CI: 0.86, 2.17) for PM2.5].
conclusionsThese findings add support to a growing body of literature on the effects of air pollution on lung cancer. In addition, they highlight variation in measurement error by pollutant and support the implementation of measurement error corrections when possible. CITATION: Hart JE, Spiegelman D, Beelen R, Hoek G, Brunekreef B, Schouten LJ, van den Brandt P. 2015. Long-term ambient residential traffic-related exposures and measurement error-adjusted risk of incident lung cancer in the Netherlands Cohort Study on Diet and Cancer. Environ Health Perspect 123:860-866; http://dx.doi.org/10.1289/ehp.1408762.
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